Condition category
Pregnancy and Childbirth
Date applied
12/09/2003
Date assigned
12/09/2003
Last edited
04/09/2015
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Karen Martin

ORCID ID

Contact details

University of Sheffield
OGN & Midwifery
Level 4
Jessop Wing
Sheffield
S10 2SF
United Kingdom

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N0059122213

Study information

Scientific title

Prospective, randomised, blind study to compare two flushing media on oocyte collection and fertilisation rates after in vitro fertilisation (IVF)

Acronym

Study hypothesis

Prospective, randomised, blind study to compare two flushing media on oocyte collection and fertilisation rates after in vitro fertilisation (IVF). The success rates of human in vitro fertilisation remain disappointingly low, only 25% of couples will take home a baby (HFEA report 1999.) The quality of eggs collected from a woman's ovaries has a significant influence on the implantation potential of any resulting embryos and therefore the chances of a patient becoming pregnant. The aims of this study are:
a. To determine whether the medium used to flush ovarian follicles during egg collection in IVF has an impact on oocyte quality, fertilisation rates and subsequent embryo development
b. To compare the use of a new complex flushing medium (Sydney IVF Follicle Flushing Buffer, COOK) with our current flushing medium, Hartmann's solution (Baxter).

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Hospitals

Trial type

Other

Patient information sheet

Not available in web format, please use the contact details below to request a patient information sheet

Condition

Pregnancy and Childbirth: In vitro fertilisation (IVF)

Intervention

Compare the use of new complex flushing medium (Sydney IVF Follicle Flushing Buffer, COOK) with our current flushing medium, Hartmann's solution (Baxter).

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Currently unavailable.

Secondary outcome measures

Not provided at time of registration

Overall trial start date

01/10/2002

Overall trial end date

01/09/2003

Reason abandoned

Eligibility

Participant inclusion criteria

Female patients, Assisted Conception Unit.

Participant type

Patient

Age group

Adult

Gender

Female

Target number of participants

Not provided at time of registration

Participant exclusion criteria

Does not meet inclusion criteria

Recruitment start date

01/10/2002

Recruitment end date

01/09/2003

Locations

Countries of recruitment

United Kingdom

Trial participating centre

University of Sheffield
Sheffield
S10 2SF
United Kingdom

Sponsor information

Organisation

Department of Health (UK)

Sponsor details

Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Sponsor type

Government

Website

http://www.doh.gov.uk

Funders

Funder type

Hospital/treatment centre

Funder name

Sheffield Teaching Hospitals NHS Foundation Trust (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

Publication citations

Additional files

Editorial Notes