Clinical symptoms and time to diagnosis in a cohort of Southern Danish children with brain tumours

ISRCTN ISRCTN88306789
DOI https://doi.org/10.1186/ISRCTN88306789
Secondary identifying numbers 01
Submission date
09/11/2010
Registration date
12/11/2010
Last edited
21/12/2011
Recruitment status
No longer recruiting
Overall study status
Completed
Condition category
Cancer
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Dr Niels Ove Illum
Scientific

Department of Paediatrics H
Odense University Hospital
Sdr Boulevard 29
Odense C
5000
Denmark

Phone +45 22 83 91 02
Email niels.illum@ouh.regionsyddanmark.dk

Study information

Study designRetrospective observational cohort study
Primary study designObservational
Secondary study designCohort study
Study setting(s)Hospital
Study typeDiagnostic
Scientific titleClinical symptoms and time to diagnosis in a cohort of Southern Danish children with brain tumours: a retrospective observational cohort study
Study objectivesTo identify time to diagnosis and first symptoms in children with brain tumours in order to improve coming diagnostic processes.
Ethics approval(s)No specific ethical requirements for this study according to Danish National Committee on Biomedical Research Ethics, as the study was observational and non-randomised only. Parent to every single participating child gave written consent.
Health condition(s) or problem(s) studiedBrain tumour
InterventionAll children living in Southern Denmark that had a brain tumour in the period from 01/10/1994 to 31/12/1999 were identified at the referral Hospital record system. Letters were forwarded to all parents, written agreement obtained and telephone interviews undertaken. Data were analysed by comparing pre-diagnosis symptoms with time from parents first encounters to diagnosis. No successive data obtained.
Intervention typeOther
Primary outcome measureClinical signs and pre-diagnosis symptomatic interval. Analyses were performed in 2010 with close August 2010.
Secondary outcome measuresNo secondary outcome measures
Overall study start date01/01/1999
Completion date31/12/1999

Eligibility

Participant type(s)Patient
Age groupChild
SexBoth
Target number of participants50
Key inclusion criteriaRetrospective study using patient records. Records of all children living in Southern Danish Region with brain tumours, from 1994 to 1999, were investigated.
Key exclusion criteriaDoes not meet inclusion criteria
Date of first enrolment01/01/1999
Date of final enrolment31/12/1999

Locations

Countries of recruitment

  • Denmark

Study participating centre

Department of Paediatrics H
Odense C
5000
Denmark

Sponsor information

Odense University Hospital (Denmark)
Hospital/treatment centre

Department of Pediatrics
Sdr Boulevard 29
Odense C
5000
Denmark

Phone +45 65 41 15 47
Email arne.hoest@ouh.regionsyddanmark.dk
Website http://www.ouh.dk/wm122110
ROR logo "ROR" https://ror.org/00ey0ed83

Funders

Funder type

University/education

No formal funding, incidental costs covered by following institutions:

No information available

Southern Danish University (Denmark) - Faculty of Medicine

No information available

Odense University Hospital (Denmark) - Department of Pediatrics

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to shareNo
IPD sharing plan summaryNot provided at time of registration
Publication and dissemination planNot provided at time of registration
IPD sharing plan

Study outputs

Output type Details Date created Date added Peer reviewed? Patient-facing?
Results article results 01/07/2011 Yes No