Strategies for the prevention of dengue (Estrategias para la prevencion del Dengue)
| ISRCTN | ISRCTN88405796 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN88405796 |
| Secondary identifying numbers | DGCD-FA2-95900-4 |
- Submission date
- 08/05/2008
- Registration date
- 12/06/2008
- Last edited
- 18/06/2009
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Infections and Infestations
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Prof Patrick Van der Stuyft
Scientific
Scientific
Institute of Tropical Medicine
Epidemiology and Disease Control Unit, Public Health Department
Nationalestraat 155
Antwerp
2000
Belgium
| pvdstuyft@itg.be |
Study information
| Study design | Single-centre cluster randomised controlled trial (blinding not possible). |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Other |
| Study type | Prevention |
| Scientific title | A cluster randomised trial evaluating community involvement in Aedes control and dengue prevention |
| Study objectives | An integrated community-based environmental management strategy is more effective in terms of reductions in entomological indices in comparison to routine Aedes control. |
| Ethics approval(s) | Ethics Committee of the Pedro Kouri Institute (Comité de ética y revision del Instituto Pedro Kouri), Havana, Cuba (affiliated to the Ministry of Health [MINSAP]), approved in September 2003 (ref: 0103015) |
| Health condition(s) or problem(s) studied | Aedes aegypti infestation/ dengue fever |
| Intervention | Intervention communities: A community-based environmental management approach combined with the routine national dengue vector control programme. Dengue control activities were identified, designed, planned and executed by the community itself, with the support of newly set-up local Community Working Groups. Control communities: Routine Aedes aegypti control programme (entomological surveillance, source reduction, selective adulticiding and health education) Total duration of interventions/ follow-up: 13 months |
| Intervention type | Other |
| Primary outcome measure | Aedes infestation levels, assessed every 11 days over the total duratin of follow-up (13 months): 1. House Indices (HI): number of houses positive for at least one container with Aedes aegypti immature stages/100 inspected houses 2. Breteau Indices (BI): number of containers positive for Aedes aegypti immature stages/100 inspected houses 3. Pupal Indices (PI): number of Aedes aegypti pupae/inhabitant In cycles of 11 days, the National Vector Control programme conducted routine entomological surveys in all dwellings of the municipality. This provided the entomological information for all clusters for the period of January 2005-February 2006. |
| Secondary outcome measures | 1. Proportion of breeding sites positive for first and second instar larvae. Data were collected as for the primary outcome measures every 11 days over 13 months. 2. Percentage of blocks (approximately 20-50 houses per block) repeatedly positive for larvae. Data were collected as for the primary outcome measures every 11 days over 13 months. 3. Level of community participation based on the Rifkin criteria, assessed 12 months after the start of interventions |
| Overall study start date | 01/09/2004 |
| Completion date | 31/12/2007 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Other |
| Sex | Both |
| Target number of participants | 32 circumscriptions of each approximately 500 houses |
| Key inclusion criteria | 1. Circumscriptions (i.e. neighbourhoods) of central urban Guantanamo 2. Community approval |
| Key exclusion criteria | 1. Circumscriptions without community approval |
| Date of first enrolment | 01/09/2004 |
| Date of final enrolment | 31/12/2007 |
Locations
Countries of recruitment
- Belgium
- Cuba
Study participating centre
Institute of Tropical Medicine
Antwerp
2000
Belgium
2000
Belgium
Sponsor information
Directorate-General for Development Co-operation (DGDC) (Belgium)
Government
Government
FOD Buitenlandse Zaken
Buitenlandse Handel en
Ontwikkelingssamenwerking
Karmelietenstraat 15
Brussels
1000
Belgium
| Website | http://www.dgic.be/en/index.html |
|---|
Funders
Funder type
Government
Directorate-General for Development Co-operation (DGDC) (Belgium) (project ref: 95900) (framework agreement between the Institute of Tropical Medicine of Belgium and of Cuba)
No information available
Ministry of Health (MINSAP) (Cuba)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 09/06/2009 | Yes | No |
