Contact information
Type
Scientific
Primary contact
Prof Stephen Bloom
ORCID ID
Contact details
6th Floor
Commonwealth Bldg.
Imperial College School of Medicine
Hammersmith Hospital
Du Cane Road
London
W12 0HS
United Kingdom
+44 (0)20 8383 3242
s.bloom@imperial.ac.uk
Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
N0016148177
Study information
Scientific title
Acronym
Study hypothesis
The short term administration of ghrelin to patients with anorexia with end stage kidney disease will result in increased appetite and calorie intake
Ethics approval
Not provided at time of registration
Study design
Randomised double blind cross over study
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Not specified
Trial type
Not Specified
Patient information sheet
Condition
Urological and Genital Diseases: Kidney disease
Intervention
Ghrelin vs placebo
Intervention type
Drug
Phase
Not Specified
Drug names
Subcutaneous Ghrelin
Primary outcome measures
Not provided at time of registration
Secondary outcome measures
Not provided at time of registration
Overall trial start date
13/03/2004
Overall trial end date
13/03/2007
Reason abandoned
Eligibility
Participant inclusion criteria
Patients with end stage kidney disease
Participant type
Patient
Age group
Not Specified
Gender
Not Specified
Target number of participants
12 volunteers
Participant exclusion criteria
Not provided at time of registration
Recruitment start date
13/03/2004
Recruitment end date
13/03/2007
Locations
Countries of recruitment
United Kingdom
Trial participating centre
6th Floor, Commonwealth Bldg.
London
W12 0HS
United Kingdom
Sponsor information
Organisation
Department of Health
Sponsor details
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
+44 20 7307 2622
dhmail@doh.gsi.org.uk
Sponsor type
Government
Website
Funders
Funder type
Government
Funder name
Hammersmith Hospital NHS Trust (UK) - NHS R&D Support
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary
2005 results on http://www.ncbi.nlm.nih.gov/pubmed/15888560
Publication citations
-
Results
Wynne K, Giannitsopoulou K, Small CJ, Patterson M, Frost G, Ghatei MA, Brown EA, Bloom SR, Choi P, Subcutaneous ghrelin enhances acute food intake in malnourished patients who receive maintenance peritoneal dialysis: a randomized, placebo-controlled trial., J. Am. Soc. Nephrol., 2005, 16, 7, 2111-2118, doi: 10.1681/ASN.2005010039.