Condition category
Urological and Genital Diseases
Date applied
30/09/2005
Date assigned
30/09/2005
Last edited
14/02/2008
Prospective/Retrospective
Retrospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Prof Stephen Bloom

ORCID ID

Contact details

6th Floor
Commonwealth Bldg.
Imperial College School of Medicine
Hammersmith Hospital
Du Cane Road
London
W12 0HS
United Kingdom
+44 (0)20 8383 3242
s.bloom@imperial.ac.uk

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

N0016148177

Study information

Scientific title

Acronym

Study hypothesis

The short term administration of ghrelin to patients with anorexia with end stage kidney disease will result in increased appetite and calorie intake

Ethics approval

Not provided at time of registration

Study design

Randomised double blind cross over study

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Not Specified

Patient information sheet

Condition

Urological and Genital Diseases: Kidney disease

Intervention

Ghrelin vs placebo

Intervention type

Drug

Phase

Not Specified

Drug names

Subcutaneous Ghrelin

Primary outcome measures

Not provided at time of registration

Secondary outcome measures

Not provided at time of registration

Overall trial start date

13/03/2004

Overall trial end date

13/03/2007

Reason abandoned

Eligibility

Participant inclusion criteria

Patients with end stage kidney disease

Participant type

Patient

Age group

Not Specified

Gender

Not Specified

Target number of participants

12 volunteers

Participant exclusion criteria

Not provided at time of registration

Recruitment start date

13/03/2004

Recruitment end date

13/03/2007

Locations

Countries of recruitment

United Kingdom

Trial participating centre

6th Floor, Commonwealth Bldg.
London
W12 0HS
United Kingdom

Sponsor information

Organisation

Department of Health

Sponsor details

Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
+44 (0)20 7307 2622
dhmail@doh.gsi.org.uk

Sponsor type

Government

Website

http://www.dh.gov.uk/Home/fs/en

Funders

Funder type

Government

Funder name

Hammersmith Hospital NHS Trust (UK) - NHS R&D Support

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2005 results on http://www.ncbi.nlm.nih.gov/pubmed/15888560

Publication citations

  1. Results

    Wynne K, Giannitsopoulou K, Small CJ, Patterson M, Frost G, Ghatei MA, Brown EA, Bloom SR, Choi P, Subcutaneous ghrelin enhances acute food intake in malnourished patients who receive maintenance peritoneal dialysis: a randomized, placebo-controlled trial., J. Am. Soc. Nephrol., 2005, 16, 7, 2111-2118, doi: 10.1681/ASN.2005010039.

Additional files

Editorial Notes