Condition category
Musculoskeletal Diseases
Date applied
05/02/2002
Date assigned
05/02/2002
Last edited
25/08/2009
Prospective/Retrospective
Prospectively registered
Overall trial status
Completed
Recruitment status
No longer recruiting

Plain English Summary

Not provided at time of registration

Trial website

Contact information

Type

Scientific

Primary contact

Dr Kenneth Muir

ORCID ID

Contact details

Public Health Medicine & Epidemiology
University of Nottingham
Queen's Medical Centre
E Floor West Block
Nottingham
NG7 2UH
United Kingdom
+44 (0)115 9709331
kenneth.Muir@nottingham.ac.uk

Additional identifiers

EudraCT number

ClinicalTrials.gov number

Protocol/serial number

M0646

Study information

Scientific title

Acronym

LIKP

Study hypothesis

Not provided at time of registration

Please note that the target number of participants was added as of 25/08/2009.

Ethics approval

Not provided at time of registration

Study design

Randomised controlled trial

Primary study design

Interventional

Secondary study design

Randomised controlled trial

Trial setting

Not specified

Trial type

Screening

Patient information sheet

Condition

Knee pain, obesity

Intervention

Participants will be randomised to a weight loss programme or an advice leaflet. In addition participants in the treatment arm will be randomised to a quadriceps exercise programme or no exercise programme.

Intervention type

Other

Phase

Not Specified

Drug names

Primary outcome measures

Not provided at time of registration

Secondary outcome measures

Not provided at time of registration

Overall trial start date

01/07/2002

Overall trial end date

30/06/2006

Reason abandoned

Eligibility

Participant inclusion criteria

Participants with knee pain will be identified in the community.

Participant type

Patient

Age group

Adult

Gender

Both

Target number of participants

389

Participant exclusion criteria

Not provided at time of registration

Recruitment start date

01/07/2002

Recruitment end date

30/06/2006

Locations

Countries of recruitment

United Kingdom

Trial participating centre

Public Health Medicine & Epidemiology
Nottingham
NG7 2UH
United Kingdom

Sponsor information

Organisation

Arthritis Research Campaign (ARC) (UK)

Sponsor details

Copeman House
St Mary's Court
St Mary's Gate
Chesterfield
Derbyshire
S41 7TD
United Kingdom
-
info@arc.org.uk

Sponsor type

Charity

Website

http://www.arc.org.uk

Funders

Funder type

Charity

Funder name

Arthritis Research Campaign (UK)

Alternative name(s)

Funding Body Type

Funding Body Subtype

Location

Results and Publications

Publication and dissemination plan

Not provided at time of registration

Intention to publish date

Participant level data

Not provided at time of registration

Results - basic reporting

Publication summary

2009 main results in http://www.ncbi.nlm.nih.gov/pubmed/19690345
2009 results of economic evaluation in http://www.ncbi.nlm.nih.gov/pubmed/19690341

Publication citations

  1. Results of economic evaluation

    Barton GR, Sach TH, Jenkinson C, Doherty M, Avery AJ, Muir KR, Lifestyle interventions for knee pain in overweight and obese adults aged > or = 45: economic evaluation of randomised controlled trial., BMJ, 2009, 339, b2273.

  2. Jenkinson CM, Doherty M, Avery AJ, Read A, Taylor MA, Sach TH, Silcocks P, Muir KR, Effects of dietary intervention and quadriceps strengthening exercises on pain and function in overweight people with knee pain: randomised controlled trial., BMJ, 2009, 339, b3170.

Additional files

Editorial Notes