Additional identifiers
EudraCT number
ClinicalTrials.gov number
Protocol/serial number
LCH 9103
Study information
Scientific title
Acronym
Study hypothesis
Not provided at time of registration
Ethics approval
Not provided at time of registration
Study design
Randomised controlled trial
Primary study design
Interventional
Secondary study design
Randomised controlled trial
Trial setting
Other
Trial type
Not Specified
Patient information sheet
Not available in web format, please use the contact details below to request a patient information sheet
Condition
Lymphoma (non-Hodgkin's)
Intervention
1. Regimen A: Chemotherapy, vinblastine with high dose methyl prednisolone
2. Regimen B: Chemotherapy, etoposide with high dose methyl prednisolone
Intervention type
Drug
Phase
Not Specified
Drug names
Chemotherapy drugs
Primary outcome measures
Not provided at time of registration
Secondary outcome measures
Not provided at time of registration
Overall trial start date
01/01/1991
Overall trial end date
31/12/1999
Reason abandoned
Eligibility
Participant inclusion criteria
1. Definitive diagnosis of multi-system Langerhans cell histocytosis
2. Age under 18 years
3. No prior treatment for Langerhans cell histocytosis
Participant type
Patient
Age group
Child
Gender
Not Specified
Target number of participants
Not provided at time of registration
Participant exclusion criteria
Not provided at time of registration
Recruitment start date
01/01/1991
Recruitment end date
31/12/1999
Locations
Countries of recruitment
United Kingdom
Trial participating centre
UKCCCR Register Co-ordinator
London
NW1 2DA
United Kingdom
Sponsor information
Organisation
Cancer Research UK (CRUK) (UK)
Sponsor details
PO Box 123
Lincoln's Inn Fields
London
WC2A 3PX
United Kingdom
+44 (0)207 317 5186
kate.law@cancer.org.uk
Sponsor type
Charity
Website
Funders
Funder type
Charity
Funder name
Cancer Research UK
Alternative name(s)
CRUK
Funding Body Type
private sector organisation
Funding Body Subtype
other non-profit
Location
United Kingdom
Funder name
United Kingdom Children's Cancer Study Group (UKCCSG)
Alternative name(s)
Funding Body Type
Funding Body Subtype
Location
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
Publication summary
1. 2001 results in http://www.ncbi.nlm.nih.gov/pubmed/11343051
Publication citations
-
Results
Gadner H, Grois N, Arico M, Broadbent V, Ceci A, Jakobson A, Komp D, Michaelis J, Nicholson S, Pötschger U, Pritchard J, Ladisch S, , A randomized trial of treatment for multisystem Langerhans' cell histiocytosis., J. Pediatr., 2001, 138, 5, 728-734, doi: 10.1067/mpd.2001.111331.