The effects of propofol and sevoflurane on electrocardiogram (ECG) indices of transmural dispersion of repolarisation in children
| ISRCTN | ISRCTN04254583 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN04254583 |
| Protocol serial number | N0206121784 |
| Sponsor | Department of Health (UK) |
| Funder | Royal Liverpool Children's NHS Trust (UK) |
- Submission date
- 12/09/2003
- Registration date
- 12/09/2003
- Last edited
- 30/04/2015
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Surgery
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr S Whyte
Scientific
Scientific
Institute of Child Health
Royal Liverpool Children's Hospital NHS Trust
Alder Hey
Eaton Road
Liverpool
L12 2AP
United Kingdom
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | The effects of propofol and sevoflurane on electrocardiogram (ECG) indices of transmural dispersion of repolarisation in children |
| Study objectives | Do the anaesthetics drugs propofol and sevoflurane affect surface electrocardiogram (ECG) indices of transmural dispersion of repolarisation? |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Surgery: Anaesthesia |
| Intervention | Patients will be randomised to receive either propofol or sevoflurane at induction of anaesthesia. |
| Intervention type | Drug |
| Phase | Not Applicable |
| Drug / device / biological / vaccine name(s) | Propofol, sevoflurane |
| Primary outcome measure(s) |
Change in T wave interval peak to end. Change in T wave interval peak to end/onset Q and T wave peak. |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/06/2003 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Child |
| Lower age limit | 1 Year |
| Upper age limit | 12 Years |
| Sex | All |
| Key inclusion criteria | American Society of Anesthesiologists (ASA) I and II infants and children aged >1 and <12 years undergoing elective surgery. |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/01/2003 |
| Date of final enrolment | 01/06/2003 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Institute of Child Health
Liverpool
L12 2AP
United Kingdom
L12 2AP
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
