Using the ISRCTN registry to track transparency
The ISRCTN registry wants to encourage trialists to follow research openness and transparency recommendations.
Registry records now display badges to highlight prospective registration, regular updating of ongoing records and posting protocols, statistical analysis plans (SAPs), data links and results to the record. The BEEP trial is an example that has several of the badges.
The transparency tracker provides a visual display of the transparency achieved by a set of records, found by a search of the registry. For any search click on 'View in tracker' to view the results in the transparency tracker. Here is an example of the transparency tracker for a search where the condition category = Cancer.
Do you think these new features are useful? We are keen to know what you think. Please complete our feedback form.
The ISRCTN registry is a primary clinical trial registry recognised by WHO and ICMJE that accepts all clinical research studies (whether proposed, ongoing or completed), providing content validation and curation and the unique identification number necessary for publication. All study records in the database are freely accessible and searchable.
ISRCTN supports transparency in clinical research, helps reduce selective reporting of results and ensures an unbiased and complete evidence base.
ISRCTN accepts all studies involving human subjects or populations with outcome measures assessing effects on human health and well-being, including studies in healthcare, social care, education, workplace safety and economic development. The registry welcomes submissions in English from any location. Studies should ideally be registered prospectively (before recruitment starts). ISRCTN also accepts studies registered retrospectively once they are underway or after completion.
Dexamethasone as an adjunctive therapy for the management of cellulitis (DEXACELL) - a randomised controlled trial in urgent secondary care
A randomized, double-blind clinical trial evaluating the efficacy and safety of the the corneo-capsular protection system (CCPS - Shamil Device) compared to standard care in cataract surgery, with primary outcomes of corneal endothelial protection and posterior capsule integrity
In UK military veterans (P) the remotely delivered Fast Imagery Reversal Script for Trauma release Protocol (I), compared to waiting list control (C) is clinically and statistically effective in reducing post-traumatic stress disorder symptoms by the minimal clinically important difference (O) at 20 weeks (T)
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