A comparative study of the effects of absorbable and non-absorbable sutures on wound healing - a prospective randomised clinical study

ISRCTN	ISRCTN05011819
DOI	https://doi.org/10.1186/ISRCTN05011819
Secondary identifying numbers	N0436146690

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English Summary

Not provided at time of registration

Miss S Jivan
Scientific

Department of Plastic Surgery
Chancellor Wing
Beckett Street
Leeds
LS9 7TF
United Kingdom

Email	Drsjivan@hotmail.com

Study design	Randomised controlled before-after trial
Primary study design	Interventional
Secondary study design	Randomised controlled trial
Study setting(s)	Hospital
Study type	Treatment
Scientific title
Study hypothesis	1. To compare and evaluate the outcome of elective surgical wound repair in the hand using absorbable and non-absorbable suture materials, in terms of wound infection, scarring, erythema and dehiscence. 2. To evaluate the outcome of wound healing in terms of patient satisfaction and comfort.
Ethics approval(s)	Not provided at time of registration
Condition	Injury, Occupational Diseases, Poisoning: Wound healing
Intervention	Absorbable vs non-absorbable sutures
Intervention type	Other
Primary outcome measure	The wounds will be assessed for quality of the scar ie erythema, scarring-hypertrophy and spread, and stitch marks. The upper and lower halves of each wound will be assessed separately. The assessor will not be told which half of the wound was closed using the prolene suture. The patients will also be asked to fill in short questionnaire relating to discomfort to stitch removal and any difference noticed by the patient within each half of the wound in the three/six month post of period.
Secondary outcome measures	Not provided at time of registration
Overall study start date	01/10/2003
Overall study end date	01/10/2004

Participant type(s)	Patient
Age group	Adult
Sex	Both
Target number of participants	50
Participant inclusion criteria	This prospective randomised clinical study will be carried out on 50 patients undergoing standard elective carpal tunnel release under local anaesthetic, in the hand surgery day unit at Leeds St. James' Hospital (under the care of the plastic surgical unit).
Participant exclusion criteria	1. Patients having re-do surgery 2. Patients undergoing combined procedures 3. Patients under the care of the orthopaedic hand surgeons 4. Patient with diabetes 5. Patients known to be on steroids or immuno-suppressants
Recruitment start date	01/10/2003
Recruitment end date	01/10/2004

Department of Plastic Surgery

Leeds
LS9 7TF
United Kingdom

Department of Health
Government

Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom

Government

Leeds Teaching Hospitals NHS Trust (UK), NHS Research and Development Support Funding

No information available

Intention to publish date
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
Publication and dissemination plan	Not provided at time of registration
IPD sharing plan

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	01/02/2005		Yes	No