Training of cognitive functions in aging population - effectiveness and use

ISRCTN	ISRCTN05615277
DOI	https://doi.org/10.1186/ISRCTN05615277
Protocol serial number	2D06013
Sponsor	Ministry of Education, Youth and Sports (Czech Republic)
Funder	Ministry of Education, Youth and Sports (Czech Republic) (ref: MSMT 2D06013)

Submission date: 18/12/2009
Registration date: 04/01/2010
Last edited: 04/01/2010

Recruitment status: No longer recruiting
Overall study status: Completed
Condition category: Mental and Behavioural Disorders

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Contact information

Dr Marek Preiss
Scientific

Prague Psychiatric Center
Ustavni 91
Prague 8
18103
Czech Republic

Study information

Primary study design	Interventional
Study design	Interventional single centre non-randomised controlled trial
Secondary study design	Non randomised controlled trial
Study type	Participant information sheet
Scientific title	Training of cognitive functions in aging population - an interventional single centre controlled trial of effectiveness and use of a memory training program
Study acronym	NPV2TP
Study objectives	1. To test the effect of a publicly available memory training program on cognitive functions and self-evaluation of the participants, measured by subjective and objective psychological methods 2. To test the effect of this memory training on relevant opinions of the participants' significant others
Ethics approval(s)	The Ethical Committee of Prague Psychiatric Center and Psychiatric Hospital Bohnice approved on the 13th December 2006 (ref: 230/06)
Health condition(s) or problem(s) studied	Cognitive status
Intervention	The intervention is a lectured memory training program in twenty 45-minute lessons in 9 block in 5 weeks in a large-group setting. It is a program that is available nationwide in the Czech Republic through a network of memory trainers, members of the Czech Society for Memory Training and Brain Jogging. Each session included: 1. Mnemonics theory and practice (mnemonic techniques: categorisation, visualisation, acrostics, acronyms, loci method, chunking, peg word system, names and faces linking method) 2. Theoretical information on brain functioning, ageing and neuroscientific findings (memory processes, hemispheric specialisation, etc.) 3. Various cognitive exercises (visuospatial skills, attention, semantic associations, anagrams, etc.) 4. Healthy ageing tips (e.g. nutrition, mental effort, social activity, physical exercise, etc.) 5. Demanding homework assessment Both groups had the same schedule of assessments: Assessment 1: baseline Assessment 2: 6 - 8 weeks later Assessment 3: 6 months later The experimental group started in April 2007 and finished in November 2007. The control group started in December 2007 and finished in July 2008. The intervention followed Assessment 1, for the experimental group only. Scientific contact details: Dr Hana Stepankova Prague Psychiatric Center Ustavni 91 18103 Prague 8 Czech Republic Email: stepankova@pcp.lf3.cuni.cz
Intervention type	Other
Primary outcome measure(s)	Measured at assessments 2 and 3: 1. Objective cognitive outcomes, measured using Auditory-Verbal Learning Test, Subtest Logical Memory of Wechsler Memory Scale III, Trail Making Test, Telephone Numbers Test, Shopping List Test 2. Subjective self-evaluation outcomes, measured using Subjective Cognitive Scale, Cognitive Failures Questionnaire and SOS-10
Key secondary outcome measure(s)	Subjective self-evaluation outcomes, measured using structured interviews, measured at assessments 2 and 3.
Completion date	31/12/2008

Eligibility

Participant type(s)	Healthy volunteer
Age group	Senior
Sex	All
Target sample size at registration	260
Key inclusion criteria	1. Community-dwelling senior citizens, aged above 50 years, either sex 2. Cognitively healthy volunteers: Mini-Mental State Examination (MMSE) greater than 26
Key exclusion criteria	Impaired cognitive or functional status
Date of first enrolment	02/04/2007
Date of final enrolment	31/12/2008

Locations

Countries of recruitment

Czech Republic

Study participating centre

Prague Psychiatric Center

Prague 8
18103
Czech Republic

Results and Publications

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan

Study outputs

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Participant information sheet	Participant information sheet	11/11/2025	11/11/2025	No	Yes
Study website	Study website	11/11/2025	11/11/2025	No	Yes