Should we remove a normal-looking appendix at a diagnostic laparoscopy in patients with acute right iliac fossa pain and no other detectable pathology?

ISRCTN	ISRCTN06195808
DOI	https://doi.org/10.1186/ISRCTN06195808
Protocol serial number	N0453122643
Sponsor	Department of Health (UK)
Funder	Central Manchester and Manchester Children's University Hospitals NHS Trust (UK)

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Mr Basil Ammori
Scientific

Central Manchester & Manchester Children's University Hospitals MRI
Manchester Royal Infirmary
Oxford Road
Manchester
M13 9WL
United Kingdom

Primary study design	Interventional
Study design	Randomised controlled trial
Secondary study design	Randomised controlled trial
Study type	Participant information sheet
Scientific title
Study objectives	Not provided at time of registration
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Appendectomy
Intervention	Randomised controlled trial comparing laprascopic removal of normal looking appendix with non-removal on diagnosis of appendicitis.
Intervention type	Procedure/Surgery
Primary outcome measure(s)	Number of patients readmitted with right lower abdominal pain during a follow up period of 12 months.
Key secondary outcome measure(s)	Not provided at time of registration
Completion date	31/12/2004

Participant type(s)	Patient
Age group	Adult
Lower age limit	18 Years
Sex	All
Key inclusion criteria	Adult subjects aged >18 years who present and are admitted to hospital acutely with right lower abdominal pain and are suspected to have acute appendicitis for which a diagnostic laparoscopy is contemplated will be considered for the study, and consented. Patients who were consented and in whom no detectable pathology is found at the time of diagnostic laparoscopy will be randomised in theatre.
Key exclusion criteria	Does not match inclusion criteria
Date of first enrolment	06/01/2003
Date of final enrolment	31/12/2004

Central Manchester & Manchester Children's University Hospitals MRI

Manchester
M13 9WL
United Kingdom

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	01/10/2009		Yes	No
Participant information sheet	Participant information sheet	11/11/2025	11/11/2025	No	Yes