Does targeted and quantified control of the microbiological environment within the ICU, using staff trained in microfibre cleaning and contamination bioload detection technology, reduce colonisation and healthcare-acquired infection?
| ISRCTN | ISRCTN06298448 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN06298448 |
| Secondary identifying numbers | 06/Q0502/91; UKCRN5751 |
- Submission date
- 24/02/2007
- Registration date
- 21/03/2007
- Last edited
- 01/02/2011
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Infections and Infestations
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Peter Wilson
Scientific
Scientific
Room 231 Windeyer Institute of Medical Sciences
University College London Hospitals
46 Cleveland Street
London
W1T 4JF
United Kingdom
| Phone | +44 (0)207 380 9516 |
|---|---|
| peter.wilson@uclh.nhs.uk |
Study information
| Study design | Prospective randomised controlled cohort study |
|---|---|
| Primary study design | Observational |
| Secondary study design | Cohort study |
| Study setting(s) | Hospital |
| Study type | Prevention |
| Participant information sheet | Not available in web format, please use the contact details below to request a patient information sheet |
| Scientific title | Microfibre cleaning and contamination bioload detection technology versus standard cleaning in a critical care unit to reduce local contamination rates: a prospective randomised controlled trial |
| Study objectives | Use of microfibre in a supervised programme of cleaning and decontamination in a critical care unit reduces local contamination rates and new colonisation of patients with Methicillin-resistant Staphylococcus aureus (MRSA) and other hospital pathogens in comparison with standard cleaning. As of 22/10/2009 details of an observational follow-up study have been added to this record. All details of this follow-up study can be found under the relevant field with the title: 'Follow-up study'. Follow-up study: A follow-up observational study was performed in which four different pathways of transmission were assessed in order to inform current Departmental policies for ward cleaning. |
| Ethics approval(s) | Joint UCL/UCLH Committee on the Ethics of Human Research approved on the 9th November 2006 (ref: 06/Q0502/91) |
| Health condition(s) or problem(s) studied | Hospital-acquired infection |
| Intervention | A total environmental cleaning system based on microfibre and governed by standard operating procedures designed to achieve microbiological control of the entire near-patient environment. Follow-up study: This follow-up study will study intensively the bacterial reservoirs within a critical care and a general ward. In addition the movement of staff from one contact surface to another will be audited together with hand hygiene. Direct observation will be used but entirely anonymised. The project will also address spread of nosocomial pathogens in the environment by cleaning materials and airborne transmission. |
| Intervention type | Other |
| Primary outcome measure | Proportion of the pooled results of all environmental swabs taken from bed areas on each day showing a target pathogen, e.g. MRSA |
| Secondary outcome measures | The rate of new acquisition by patients of MRSA and other target pathogens |
| Overall study start date | 02/04/2007 |
| Completion date | 05/04/2008 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Other |
| Sex | Both |
| Target number of participants | 3 intensive care units, 14000 patient days, 4000 patients |
| Key inclusion criteria | All patients admitted to the critical care units of UCLH and Royal Free Hospitals. The critical care units are randomised to microfibre or standard cleaning. There is no patient intervention other than recording any infections developed. |
| Key exclusion criteria | Does not meet inclusion criteria |
| Date of first enrolment | 02/04/2007 |
| Date of final enrolment | 05/04/2008 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
Room 231 Windeyer Institute of Medical Sciences
London
W1T 4JF
United Kingdom
W1T 4JF
United Kingdom
Sponsor information
National Institute for Health Research (NIHR) (UK)
Government
Government
PO Box 407
Teddington
TW11 0XX
United Kingdom
| Phone | +44 (0)20 8943 8990 |
|---|---|
| Joanne.Martin@nihr-ccf.org.uk | |
| Website | http://www.nihr-ccf.org.uk |
"ROR" |
https://ror.org/0187kwz08 |
Funders
Funder type
Government
National Institute for Health Research (NIHR) (UK) - HCAI Technology Innovation Programme (ref: 0140028)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/04/2011 | Yes | No |
