The effectiveness and cost-effectiveness of public access defibrillation in urban and rural populations in Northern Ireland

ISRCTN	ISRCTN07286796
DOI	https://doi.org/10.1186/ISRCTN07286796
Protocol serial number	COM/2371/03
Sponsor	The Research and Development Office for Health and Personal Social Services in Northern Ireland (UK)
Funder	The Research and Development Office for Health and Personal Social Services in Northern Ireland (UK)

Submission date: 20/01/2006
Registration date: 30/01/2006
Last edited: 18/03/2008

Recruitment status: No longer recruiting
Overall study status: Completed
Condition category: Circulatory System

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Prof Frank Kee
Scientific

QUB Centre For Clinical and Population Science
1st Floor Mulhouse building
Royal Victoria Hospital
Grosvenor road
Belfast
BT12 6BA
United Kingdom

Phone	+44 (0)28 90632746
Email	f.kee@qub.ac.uk

Study information

Primary study design	Interventional
Study design	An observational study for one year followed by an intervention using public access defibrillation on the cohort
Secondary study design	Cohort study
Scientific title
Study acronym	Northern Ireland Public Access Defibrillation (NIPAD)
Study objectives	Training laypersons such as first responders and police officers to carry and use automated external defibrillators to attend the scene of out-of-hospital sudden cardiac arrests will result in the resuscitation of additional patients by a reduction in the response time compared to the existing emergency medical service response.
Ethics approval(s)	Ethics approval received from the Northern Ireland Research Ethics Committee on the 26th March 2003 (ref: 47/03).
Health condition(s) or problem(s) studied	Out-of-hospital sudden cardiac arrest
Intervention	Training lay cardiac first responders and police officers to carry and use automated external defibrillators in response to sudden out-of-hospital cardiac arrest in fixed and mobile locations.
Intervention type	Other
Primary outcome measure(s)	1. Survival after hospital discharge following out-of-hospital sudden cardiac arrest 2. Cost-effectiveness of public access defibrillation in the study areas
Key secondary outcome measure(s)	1. Reduction in response time compared to existing emergency medical services 2. Return of spontaneous circulation 3. The modelling of the results to Northern Ireland as a whole using a spatial modelling approach 4. The modelling of the effectiveness and cost-effectiveness of public access defibrillation across Northern Ireland
Completion date	03/04/2006

Eligibility

Participant type(s)	Patient
Age group	Adult
Sex	All
Target sample size at registration	300
Key inclusion criteria	All patients with a presumed out-of-hospital sudden cardiac arrest over the age of 14 in Antrim, Ballymena, Magherafelt and North and West Belfast district council areas of Northern Ireland.
Key exclusion criteria	Out-of-hospital sudden deaths due to non-cardiac causes including trauma, drowning, overdose, poisoning and fire.
Date of first enrolment	01/01/2004
Date of final enrolment	03/04/2006

Locations

Countries of recruitment

United Kingdom
Northern Ireland

Study participating centre

QUB Centre For Clinical and Population Science

Belfast
BT12 6BA
United Kingdom

Results and Publications

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan

Study outputs

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	Results	01/03/2008		Yes	No
Study website	Study website	11/11/2025	11/11/2025	No	Yes