The effect of continuous positive airway pressure (CPAP) and non-invasive positive pressure ventilation (NIPPV) in acute cardiogenic pulmonary oedema (ACPO)
| ISRCTN | ISRCTN07448447 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN07448447 |
| Protocol serial number | HTA 01/43/01 |
| Sponsor | Department of Health (UK) |
| Funder | NIHR Health Technology Assessment Programme - HTA (UK) |
- Submission date
- 25/04/2003
- Registration date
- 25/04/2003
- Last edited
- 02/08/2010
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Circulatory System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Alasdair James Gray
Scientific
Scientific
Emergency Department
Royal Infirmary of Edinburgh
51 Little France Crescent
Old Dalkeith Road
School of Health and Related Research
Edinburgh
EH16 4SA
United Kingdom
| Phone | +44 (0)131 242 1334 |
|---|---|
| alasdair.gray@luht.scot.nhs.uk |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study acronym | 3CPO |
| Study objectives | To assess the clinical effectiveness of non-invasive ventilation against standard therapy alone More details can be found at http://www.hta.ac.uk/project/1338 Protocol can be found at http://www.hta.ac.uk/protocols/200100430001.pdf |
| Ethics approval(s) | Not requested at time of registration |
| Health condition(s) or problem(s) studied | Cardiovascular diseases: Heart disease |
| Intervention | Continuous Positive Airway Pressure (CPAP) versus Non-Invasive Positive Pressure Ventilation (NIPPV) Please note that, as of 28 January 2008, the anticipated end date of this trial was updated from 31 December 2007 to 30 April 2008. Please note that as of 12th June 2007, the anticipated end date of this trial was extended to 31st December 2007 (Anticipated end date provided at time of registration: 30 June 2006). Recruitment to this trial was closed on 30 April 2007. |
| Intervention type | Other |
| Primary outcome measure(s) |
Added on the 12th June 2007: |
| Key secondary outcome measure(s) |
Added on the 12th June 2007: |
| Completion date | 30/04/2008 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Not Specified |
| Target sample size at registration | 1200 |
| Key inclusion criteria | 1. More than 16 years 2. Acute Cardiogenic Pulmonary Oedema (ACPO) principal clinical complaint 3. Confirmed diagnosis of ACPO |
| Key exclusion criteria | 1. Patients needing immediate life-saving interventions 2. Inability to provide informed consent |
| Date of first enrolment | 01/06/2003 |
| Date of final enrolment | 30/04/2008 |
Locations
Countries of recruitment
- United Kingdom
- Scotland
Study participating centre
Emergency Department
Edinburgh
EH16 4SA
United Kingdom
EH16 4SA
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 10/07/2008 | Yes | No | |
| Results article | results | 01/07/2009 | Yes | No | |
| Results article | results | 01/08/2010 | Yes | No |
