Pharmacists' review of medicine during admission to hospital

ISRCTN	ISRCTN08043800
DOI	https://doi.org/10.1186/ISRCTN08043800
Protocol serial number	N/A
Sponsor	Region Zealand Hospital Pharmacy (Region Sjaelland Sygehusapoteket) (Denmark)
Funders	Region Zealand (Region Sjaelland) (Denmark), Region Zealand Hospital Pharmacy (Region Sjaelland Sygehusapoteket) (Denmark), Hospital pharmacists and Amgros' Research and Development (Sygehusapotekernes- og Amgros Forsknings- og udviklingsfond) (Denmark)

Submission date: 04/03/2010
Registration date: 06/04/2010
Last edited: 17/11/2010

Recruitment status: No longer recruiting
Overall study status: Completed
Condition category: Other

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Contact information

Ms Trine R. H. Nielsen
Scientific

Ringstedgade 63
Naestved
DK-4700
Denmark

Email	trn@regionsjaelland.dk

Study information

Primary study design	Interventional
Study design	Multicentre interventional prospective randomised clinical controlled trial
Secondary study design	Randomised controlled trial
Study type	Participant information sheet
Scientific title	Pharmaceutical optimization of the medication process during admission to hospital: A multicentre, randomised, controlled trial
Study acronym	POMP
Study objectives	A pharmaceutical intervention consisting of: review and use of patient 'sown drugs, secondary medication history, medication review and entry of proposed prescriptions in the electronic medication system will reduce the number of adverse drug events during hospital stay.
Ethics approval(s)	Approval by the Danish Ethics Committee is not applicable since the study is not of biomedical nature
Health condition(s) or problem(s) studied	In-hospital adverse drug events
Intervention	Please note that the anticipated end date for this trial has been extended from 01/11/10 to 31/03/10. Intervention Group 1. Review and use of patient own drugs by clinical pharmacist. 2. Clinical pharmacist taking secondary medication history. 3. Medication review by clinical pharmacist. 4. Entry of proposed prescriptions in the electronic medication system by pharmacist, ready for approval by doctor. The intervention takes place on the day the patient is admitted, and the duration of the intervention is approximately 1.5 hours. Control Group Standard care with no pharmacist involvement There is no follow up examination, but re-admission rates will be noted for 1 year post intervention.
Intervention type	Other
Primary outcome measure(s)	Number of patients with in-hospital adverse drug events, detected by Adverse Drug Event Trigger Tool.
Key secondary outcome measure(s)	1. Length of hospital stay 2. Number of readmissions during the first year after admission 3. Direct cost for the hospital
Completion date	31/03/2011

Eligibility

Participant type(s)	Patient
Age group	Adult
Lower age limit	18 Years
Sex	All
Target sample size at registration	648
Key inclusion criteria	1. Patients being admitted to an internal medicine ward 2. Age 18 years or more 3. Taking 4 types of medicine or more each day 4. Able to understand participant's information written in Danish
Key exclusion criteria	1. Patients transferred from other hospitals in the area 2. Dying or terminally ill patients 3. Patients being discharged within 48 hours from admission
Date of first enrolment	08/03/2010
Date of final enrolment	31/03/2011

Locations

Countries of recruitment

Denmark

Study participating centre

Ringstedgade 63

Naestved
DK-4700
Denmark

Results and Publications

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan

Study outputs

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Participant information sheet	Participant information sheet	11/11/2025	11/11/2025	No	Yes