Towards a more green and healthy food culture - Organic food, sustainability and health on one plate

ISRCTN	ISRCTN11365927
DOI	https://doi.org/10.1186/ISRCTN11365927
ClinicalTrials.gov (NCT)	Nil known
Clinical Trials Information System (CTIS)	Nil known
Protocol serial number	34009-22-2036
Sponsor	Technical University of Denmark
Funders	Organic RDD 8 programme, coordinated by International Centre for Research in Organic Food Systems (ICROFS), Danish Ministry of Food, Agriculture and Fisheries

Submission date: 10/11/2025
Registration date: 03/12/2025
Last edited: 17/11/2025

Recruitment status: Recruiting
Overall study status: Ongoing
Condition category: Nutritional, Metabolic, Endocrine

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Record updated in last year

Plain English summary of protocol

Background and study aims
Our food choices affect both our health and the planet. The OnePlate study is looking at whether eating more organic and plant-based foods, following Danish dietary guidelines, can help families eat in a way that’s better for their health and the environment.

Who can participate?
Families with children aged 3 to 17 years old can take part.

What does the study involve?
Families who join the study will be randomly placed into one of two groups. One group will continue eating as usual. The other group will follow the OnePlate diet for six weeks. This group will receive:
-Weekly meal planner posters
-A recipe book with tips and meal ideas
-A children’s activity booklet to make learning about food fun
-A selection of basic ingredients used in the recipes
-Weekly email updates with helpful information
-All families will also be able to buy food online at a discount.

What are the possible benefits and risks of participating?
The study aims to help families make healthier and more sustainable food choices. The only known risk is a small chance of bruising or infection from blood samples taken during the study.

Where is the study run from?
The study is based in Copenhagen, Denmark.

When is the study starting and how long is it expected to run for?
It starts in October 2025 and will run until July 2026.

Who is funding the study?
The study is funded by the Green Growth and Development programme (GUDP).

Who is the main contact?
Dr Anne Dahl Lassen, adla@food.dtu.dk

Contact information

Dr Anne Dahl Lassen
Public, Scientific, Principal investigator

Kemitorvet, Building 201
Kgs. Lyngby
2800
Denmark

ORCID ID	0000-0002-3262-3611
Phone	+45 31425789
Email	adla@food.dtu.dk

Study information

Primary study design	Interventional
Study design	Randomized non-blinded controlled study among healthy Danish families
Secondary study design	Randomised controlled trial
Study type	Participant information sheet
Scientific title	Organic food, Sustainability and Health on one plate — a randomized controlled trial among Danish families
Study acronym	OnePlate
Study objectives	The objective of the OnePlate study is to evaluate the effectiveness and feasibility a dietary approach that combines organic food with a healthy, plant-rich diet among Danish families with children. More specifically the OnePlate project aims to: 1. Evaluate the effectiveness of the OnePlate diet on both human health (e.g. pesticide exposure and indicators of cardiometabolic disease) and planetary health (e.g. climate footprint, land use, and biodiversity). 2. Gain real-world insights into how families implement the OnePlate concept, as well as identifying barriers, opportunities, and motivational factors influencing their transition.
Ethics approval(s)	Approved 23/05/2025, Danish National Ethics Committee (Borgervænget 3, st., Copenhagen, 2100, Denmark; +45 38 66 63 95; vek@regionh.dk), ref: H-24047427
Health condition(s) or problem(s) studied	Prevention of cardiometabolic diseases and reduction of environmental impact of food intake among healthy families
Intervention	The study is designed as a free-living, family-based, two-arm, parallel randomized controlled trial, comparing 1) a plant-rich and organic diet (intervention group) to 2) the habitual diet (control group) of individuals of the families, through a six-week intervention period. Randomization of families was performed using a random number generator (through EasyTrial) Families in the intervention group will receive a box including 1. Weekly Meal Planner Posters 2. a OnePlate Book with recipes, describing the OnePlate concept including guidelines and tips for each meal of the day and three weekly dinner plans to be repeated twice during the six-week intervention 3. a Children’s activity booklet to engage young children with small tasks to promote knowledge and curiosity in a fun way and 4. a selection of basic ingredients used in the OnePlate recipes. Furthermore, intervention families will receive e-mail newsletters for regular information approximately one post per week throughout the intervention period. All families will have the opportunity to purchase foods online with discount.
Intervention type	Behavioural
Primary outcome measure(s)	1. Plasma total cholesterol measured from fasting blood samples from all adults at baseline and follow-up 2. Pesticide metabolites excretion measured from first-morning urine samples on three days at baseline and follow-up
Key secondary outcome measure(s)	At baseline and follow-up: 1. Ratio of animal-sourced vs. plant-sourced proteins (AP) in the diet (adults and children using a digital seven-day dietary record) 2. Other cardiometabolic disease-related risk factors (LDL cholesterol, HDL cholesterol, triglycerides, fasting glucose and insulin levels, blood pressure, anthropometric data and hsCRP) 3. Other dietary intake data: food groups (e.g. legumes, vegetables, fruits, meat, fish, dairy), macronutrients, micronutrients, and energy intake (using a digital seven-day dietary record) 4. Iron status (hemoglobin and ferritin) and vitamin B12 (cobalamin) (blood samples adults) 5. Sodium and potassium excretion (urine samples children and adults) 6. Parental attitudes, practices, self-efficacy and perceived social norms 7. Sustainability of the diet based on climate impact, land-use and biodiversity loss At follow-up: 8. Use and acceptability of the intervention components measured by a questionnaire among intervention families 9. Interviews post-intervention among selected intervention families
Completion date	30/06/2027

Eligibility

Participant type(s)	Healthy volunteer
Age group	Mixed
Lower age limit	3 Years
Upper age limit	70 Years
Sex	All
Target sample size at registration	80
Key inclusion criteria	1. Families and households with at least one participating parent and at least one participating child aged 3-17 years. 2. Families are eligible if they have a regular consumption of meat (meat or fish normally more than 4 times a week) and a majority of their fruits, vegetables, cereals, and bread purchases originates from conventional farming, i.e. at least half of the plant-based foods and products purchased in the household should be non-organic (self-reported)
Key exclusion criteria	1. Pregnancy 2. Diabetes type I and type II if medicated 3. Cancer treatment or recently had a major surgery 4. Users of weight loss medication (e.g. Wegovy) 5. Severe anaemia
Date of first enrolment	18/09/2025
Date of final enrolment	31/07/2026

Locations

Countries of recruitment

Denmark

Study participating centre

DTU Food

Henrik Dams Allé
Kgs Lyngby
DK-2800
Denmark

Results and Publications

Individual participant data (IPD) Intention to share	Yes
IPD sharing plan summary	Available on request
IPD sharing plan	Available on request from adla@food.dtu.dk

Study outputs

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Participant information sheet	Participant information sheet	11/11/2025	11/11/2025	No	Yes
Study website	Study website	11/11/2025	11/11/2025	No	Yes

Editorial Notes

10/11/2025: Trial's existence confirmed by International Centre for Research in Organic Food Systems (ICROFS).