The effects of krill oil on resistance exercise
| ISRCTN | ISRCTN11524409 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN11524409 |
| Secondary identifying numbers | KrillOil002 |
- Submission date
- 27/10/2017
- Registration date
- 31/10/2017
- Last edited
- 16/10/2018
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Nutritional, Metabolic, Endocrine
Plain English summary of protocol
Background and study aims
Resistance training describes a type of training where you move against a force that resists your movement. Krill Oil is a supplement that could be helpful to those who are doing resistance training.
The aim of this study is to investigate the effect of a nutritional intervention, Krill Oil, in combination with resistance training on muscular health in healthy participants.
Who can participate?
Males aged 18 to 30 years old who are currently doing resistance training at least two times per week for the past six months.
What does the study involve?
Participants undergo a resistance training program (programmed, non-linear training split) four days per week for a period of 8 weeks. Participants are randomly allocated to one of two groups. Those in the first group receive 3grams of a placebo (a dummy capsule) that contains safflower oil. Those in the second group receive the Krill oil (3 grams) capsule. Supplements are consumed prior to workouts on training days while eating breakfast on non-training days. Participants are assessed for their body composition and muscle strength after eight weeks.
What are the possible benefits and risks of participating?
Participants may benefit from an increase in lean body mass and strength. Participation in exercise includes the potential risk of injury.
Where is the study run from?
Applied Science and Performance Institute (USA)
When is the study starting and how long is it expected to run for?
January 2016 to December 2016
Who is funding the study?
Rimfrost USA (USA)
Who is the main contact?
Dr Jacob Wilson
Contact information
Scientific
5850 W Cypress Street
Tampa
33607
United States of America
Study information
| Study design | Single-center randomised double-blind placebo-controlled parallel interventional study |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised parallel trial |
| Study setting(s) | Other |
| Study type | Quality of life |
| Participant information sheet | No participant information sheet available. |
| Scientific title | The effects of krill oil supplementation combined with resistance training on body composition and athletic performance |
| Study objectives | The aim of this study is to investigate the ability of Krill Oil to augment resistance training-induced changes in body composition and performance. |
| Ethics approval(s) | IntegReview IRB, Austin, TX, 14/03/2016, ref: Protocol Number: 7952 |
| Health condition(s) or problem(s) studied | Healthy volunteers |
| Intervention | Participants undergo a resistance training program (programmed, non-linear training split) four days per week for a period of 8 weeks. Participants are allocated to one of two groups. Those in the first group receive 3 grams of Placebo (safflower oil) in a softgel 6500 mg capsule. Those in the second group receive 3 grams of Krill (Euphausia superba) Oil (Rimfrost Sublime, Rimfrost USA LLC, Merry Hill, NC, USA, Lot 8723-15-01-03), administered as 6 500mg softgel capsules. Supplements are consumed pre-workout on training days, and with breakfast on non-training days. Participants are followed up for their body composition using the whole-body Dual-Energy X-ray Absorptiometry (DXA) at baseline and 8 weeks. Participants are assessed for their strength using one repetition maximum (1RM) on a bench press and leg press at baseline and 8 weeks. |
| Intervention type | Supplement |
| Primary outcome measure | 1. Body composition is measured using the whole-body Dual-Energy X-ray Absorptiometry (DXA) at baseline and 8 weeks 2. Strength is measured using one repetition maximum (1RM) on a bench press and leg press at baseline and 8 weeks |
| Secondary outcome measures | 1. Perceptual Measures is measured using perceived recovery at beginning and end of every week 2. Cognition is measured using a Stroop Test at baseline and eight weeks 3. Safety is measured using comprehensive metabolic panel (CMP) at baseline and eight weeks 4. Complete blood count (CBC) and lipid panels is measured using blood tests at baseline and eight weeks |
| Overall study start date | 01/01/2016 |
| Completion date | 31/12/2016 |
Eligibility
| Participant type(s) | Healthy volunteer |
|---|---|
| Age group | Adult |
| Lower age limit | 18 Years |
| Sex | Male |
| Target number of participants | 21 |
| Key inclusion criteria | 1. Males 18 to 30 years of age 2. Resistance training at least 2 times per week for the past six months 3. Minimum of 1 year of training experience active 4. Currently resistance training |
| Key exclusion criteria | 1. Free of musculoskeletal, metabolic, and respiratory disorders 2. Free of cardiovascular disease 3. No musculoskeletal injuries with the last six months 4. No history of smoking or drug use 5. No history of excessive alcohol consumption 6. Not taking prescription medication 7. Have not used a fish oil-, thermogenic-, protein-, amino acid-, or creatine supplement within the prior two months 8. Have not habitually used caffeine (e.g. more than 2 cups of coffee per day) |
| Date of first enrolment | 15/03/2016 |
| Date of final enrolment | 01/11/2016 |
Locations
Countries of recruitment
- United States of America
Study participating centre
33607
United States of America
Sponsor information
Industry
841 Avoca Farm Road
Merry Hill
27957
United States of America
"ROR" |
https://ror.org/02q6tz689 |
|---|
Funders
Funder type
Industry
No information available
Results and Publications
| Intention to publish date | 01/04/2018 |
|---|---|
| Individual participant data (IPD) Intention to share | Yes |
| IPD sharing plan summary | Available on request |
| Publication and dissemination plan | Planned publication in a high-impact peer reviewed journal. |
| IPD sharing plan | The datasets generated during and/or analysed during the current study are/will be available upon request from Dr Jacob M Wilson, jwilson@theaspi.com. |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 26/04/2018 | Yes | No |
Editorial Notes
16/10/2018: Publication reference added.
