Does magnesium augment the pain relieving effects of low dose intravenous lidocaine (lignocaine) in patients with chronic non malignant pain? A randomised double-blind crossover study
| ISRCTN | ISRCTN12273453 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN12273453 |
| Protocol serial number | N0263139706 |
| Sponsor | Department of Health |
| Funder | University College London Hospitals NHS Trust (UK) |
- Submission date
- 30/09/2004
- Registration date
- 30/09/2004
- Last edited
- 22/04/2015
- Recruitment status
- Stopped
- Overall study status
- Stopped
- Condition category
- Signs and Symptoms
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr A P Baranowski
Scientific
Scientific
Pain Management Department
National Hospital for Neurology & Neurosurgery
Queen Square
London
WC1N 3BG
United Kingdom
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised double-blind crossover study |
| Secondary study design | Randomised cross over trial |
| Scientific title | Does magnesium augment the pain relieving effects of low dose intravenous lidocaine (lignocaine) in patients with chronic non malignant pain? A randomised double-blind crossover study |
| Study objectives | Can the addition of magnesium sulphate to systemic low dose lidocaine treatment for chronic pain improve the intensity and duration of pain reduction? |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Signs and Symptoms: Pain |
| Intervention | 1. Lignocaine 2. Non lignocaine |
| Intervention type | Other |
| Primary outcome measure(s) |
Change in pain score following treatment. |
| Key secondary outcome measure(s) |
Number of patients receiving >50% pain relief, pain relief intensity and sleep interference, duration of pain relief, number and frequency of adverse events, effect on blood pressure. |
| Completion date | 31/03/2005 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target sample size at registration | 20 |
| Key inclusion criteria | 20 patients from Pain Management |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/04/2004 |
| Date of final enrolment | 31/03/2005 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
National Hospital for Neurology & Neurosurgery
London
WC1N 3BG
United Kingdom
WC1N 3BG
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
