Does magnesium augment the pain relieving effects of low dose intravenous lidocaine (lignocaine) in patients with chronic non malignant pain? A randomised double-blind crossover study
| ISRCTN | ISRCTN12273453 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN12273453 |
| Secondary identifying numbers | N0263139706 |
- Submission date
- 30/09/2004
- Registration date
- 30/09/2004
- Last edited
- 22/04/2015
- Recruitment status
- Stopped
- Overall study status
- Stopped
- Condition category
- Signs and Symptoms
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr A P Baranowski
Scientific
Scientific
Pain Management Department
National Hospital for Neurology & Neurosurgery
Queen Square
London
WC1N 3BG
United Kingdom
Study information
| Study design | Randomised double-blind crossover study |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised cross over trial |
| Study setting(s) | Not specified |
| Study type | Treatment |
| Scientific title | Does magnesium augment the pain relieving effects of low dose intravenous lidocaine (lignocaine) in patients with chronic non malignant pain? A randomised double-blind crossover study |
| Study objectives | Can the addition of magnesium sulphate to systemic low dose lidocaine treatment for chronic pain improve the intensity and duration of pain reduction? |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Signs and Symptoms: Pain |
| Intervention | 1. Lignocaine 2. Non lignocaine |
| Intervention type | Other |
| Primary outcome measure | Change in pain score following treatment. |
| Secondary outcome measures | Number of patients receiving >50% pain relief, pain relief intensity and sleep interference, duration of pain relief, number and frequency of adverse events, effect on blood pressure. |
| Overall study start date | 01/04/2004 |
| Completion date | 31/03/2005 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target number of participants | 20 |
| Key inclusion criteria | 20 patients from Pain Management |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/04/2004 |
| Date of final enrolment | 31/03/2005 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
National Hospital for Neurology & Neurosurgery
London
WC1N 3BG
United Kingdom
WC1N 3BG
United Kingdom
Sponsor information
Department of Health
Government
Government
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Website | http://www.dh.gov.uk/Home/fs/en |
|---|
Funders
Funder type
Government
University College London Hospitals NHS Trust (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
