Carbon monoxide alarm use by Emergency Department patients

ISRCTN	ISRCTN12562718
DOI	https://doi.org/10.1186/ISRCTN12562718
IRAS number	306275
Secondary identifying numbers	IRAS 306275, CPMS 51448

Submission date: 27/11/2021
Registration date: 06/05/2022
Last edited: 03/03/2025

Recruitment status: No longer recruiting
Overall study status: Completed
Condition category: Other

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Background and study aims
Carbon monoxide is a colourless odourless gas that can cause symptoms such as headache, muscle aches and flu-like symptoms. Carbon monoxide exposure leads to 4000 attendances to Emergency departments each year and can cause long-term health problems. Having a carbon monoxide alarm installed in homes can help with the early detection of carbon monoxide and reduce the risk of exposure. Not everyone has a carbon monoxide alarm in their homes and the aim of this study is to find out if there are differences in those who have alarms compared to those that do not so they can provide tailored information on carbon monoxide alarm use to those that need it

Who can participate?
Patients or carers attending the Emergency Department aged 16 years or over.

What does the study involve?
The study involves answering a survey on the internet either on the patients’ mobile phone or a study tablet device. The survey includes 21 questions asking about the presence and location of carbon monoxide alarms and will also include questions about the type of home, household income and ethnicity

What are the possible benefits and risks of participating?
There will be no direct benefits related to participation. Indirect benefits include contributing to a better understanding of the use of carbon monoxide in the home. The results will be used to target future public health information to those who do not have alarms installed in their homes.

Where is the study run from?
St George’s University Hospitals NHS Foundation Trust (UK)

When is the study starting and how long is it expected to run for?
June 2021 to March 2023

Who is funding the study?
Carbon Monoxide Research Trust (UK)

Who is the main contact?
Prof. Heather Jarman
Heather.jarman@stgeorges.nhs.uk

Study website

Contact information

Prof Heather Jarman
Scientific

Emergency Department Clinical Research Unit
Emergency Department
St George's University Hospitals NHS Foundation Trust
Blackshaw Road
London
SW17 0QT
United Kingdom

ORCID ID	0000-0002-4820-3291
Phone	+44 (0)208 725 4849
Email	heather.jarman@stgeorges.nhs.uk

Prof Heather Jarman
Public

Emergency Department Clinical Research Unit
Emergency Department
St George's University Hospitals NHS Foundation Trust
Blackshaw Road
London
SW17 0QT
United Kingdom

Phone	+44 (0208 725 4849
Email	heather.jarman@stgeorges.nhs.uk

Study information

Study design	Multicentre prospective cross-sectional observational survey
Primary study design	Observational
Secondary study design	Cross sectional study
Study setting(s)	Hospital
Study type	Prevention
Participant information sheet	Not available in web format, please use the contact details to request a participant information sheet
Scientific title	A survey of carbon monoxide alarm use in patients attending the Emergency Department (EDCO-M)
Study acronym	EDCO-M
Study objectives	What is the prevalence of carbon monoxide alarms?
Ethics approval(s)	Approved 21/12/2021, HRA Proportionate Review Sub-Committee (London - Westminster Research Ethics Committee, Equinox House, City Link, Nottingham, NG2 4LA, UK; +44 (0)20 7104 8066; westminster.rec@hra.nhs.uk), REC ref: 21/PR/1657
Health condition(s) or problem(s) studied	Carbon monoxide alarm use
Intervention	The study involves answering a survey on the internet either on the patients’ mobile phone or a study tablet device. The survey includes 21 questions asking about the presence and location of carbon monoxide alarms and will also include questions about the type of home, household income and ethnicity.
Intervention type	Other
Primary outcome measure	Prevalence of fitted carbon monoxide alarms in patients' homes measured by asking if households they have a carbon monoxide alarm at a single timepoint (survey completion)
Secondary outcome measures	There are no secondary outcome measures
Overall study start date	01/06/2021
Completion date	09/03/2023

Eligibility

Participant type(s)	Patient
Age group	Adult
Sex	Both
Target number of participants	6,000
Total final enrolment	6043
Key inclusion criteria	1. Patient or carer aged 16 years or over 2. Parent or carer of a child under 16 years 3. Participant is willing and able to give informed consent for participation in the study 4. Participant currently resides in the UK
Key exclusion criteria	1. Unable to read and understand the study information or consent process due to injury/illness or language barrier 2. Treating clinician (doctor or nurse) feels that it is not appropriate to approach the patient to participate
Date of first enrolment	01/01/2022
Date of final enrolment	09/03/2023

Locations

Countries of recruitment

England
United Kingdom

Study participating centres

St George's Hospital

St George's University Hospitals NHS Foundation Trust
Blackshaw Road
London
SW17 0QT
United Kingdom

St Helier Hospital

Epsom and St Helier University Hospitals NHS Trust
Wrythe Lane
Carshalton
London
SM5 1AA
United Kingdom

Sponsor information

St George's, University of London
University/education

Cranmer Terrace
London
SW17 0RE
England
United Kingdom

Phone	+44 (0)208 725 4986
Email	research@sgul.ac.uk
Website	http://www.sgul.ac.uk/
"ROR"	https://ror.org/040f08y74

Funders

Funder type

Charity

Carbon Monoxide Research Trust

No information available

Results and Publications

Intention to publish date	31/12/2023
Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not expected to be made available
Publication and dissemination plan	1. Planned publication in a peer-reviewed journal 2. Internal report 3. Conference publication 4. Publication on website
IPD sharing plan	Participant-level data will not be available as ethics approval to share the data has not been given

Study outputs

Output type	Date created	Date added	Peer reviewed?	Patient-facing?
Protocol article	16/11/2022	18/11/2022	Yes	No
HRA research summary		28/06/2023	No	No
Basic results		03/03/2025	No	No

Additional files

ISRCTN12562718_BasicResults.pdf

Editorial Notes

03/03/2025: Basic Results uploaded.
09/03/2023: The following changes were made to the trial record:
1. The overall end date was changed from 30/04/2023 to 09/03/2023.
2. The recruitment end date was changed from 31/03/2023 to 09/03/2023.
3. The target number of participants was changed from 4000 to 6000.
4. The total final enrolment was added.
04/01/2023: The following updates have been made:
1. The recruitment end date has been changed from 31/12/2022 to 31/03/2023.
2. The overall trial end date has been changed from 31/03/2023 to 30/04/2023 and the plain English summary updated accordingly.
3. The intention to publish date has been changed from 31/03/2023 to 31/12/2023.
4. Ethics approval added.
18/11/2022: Publication reference added.
07/06/2022: Internal review.
03/12/2021: Trial's existence confirmed by the HRA.