Therapeutic efficacy of slow repetitive transcranial magnetic stimulation (rTMS) of the right prefrontal cortex in anxiety disorders. A randomised double-blind, placebo-controlled trial.
| ISRCTN | ISRCTN13013591 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN13013591 |
| Protocol serial number | N0038110439 |
| Sponsor | Department of Health (UK) |
| Funder | Avon and Wiltshire Mental Health Partnership NHS Trust (UK) |
- Submission date
- 12/09/2003
- Registration date
- 12/09/2003
- Last edited
- 24/09/2013
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Mental and Behavioural Disorders
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Ray Goggins
Scientific
Scientific
The Burden Centre
Frenchay Hospital
Frenchay Park Road
Bristol
BS16 1JB
United Kingdom
| Phone | +44 (0)117 918 6710 |
|---|
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | Do slow rTMS reduce anxiety symptoms by at least 20% as rated by the Hamilton anxiety scale (HAM-A) and Anxiety T scores on the SCL-90-R? |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Mental and Behavioural Disorders: Anxiety disorders |
| Intervention | Randomised controlled trial of intervention. 1. Repetitive transcranial magnetic stimulation (rTMS) 2. Placebo sham rTMS |
| Intervention type | Other |
| Primary outcome measure(s) |
Clinical ratings assessed at baseline, at five treatments, and at seven treatments. |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 18/02/2004 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | All |
| Target sample size at registration | 24 |
| Key inclusion criteria | 24 patients meeting Diagnostic and Statistical Manual of Mental Disorders, Fourth edition (DSM-IV) criteria for anxiety disorder. |
| Key exclusion criteria | Does not match inclusion criteria |
| Date of first enrolment | 01/09/2002 |
| Date of final enrolment | 18/02/2004 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
The Burden Centre
Bristol
BS16 1JB
United Kingdom
BS16 1JB
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
