Effectiveness of a structured educational intervention on registered nurses’ knowledge, attitudes, and practices toward adherence to pressure injury prevention

ISRCTN	ISRCTN14515418
DOI	https://doi.org/10.1186/ISRCTN14515418
Sponsor	King Saud University
Funder	King Saud University

Submission date: 19/12/2025
Registration date: 05/01/2026
Last edited: 05/01/2026

Recruitment status: No longer recruiting
Overall study status: Completed
Condition category: Other

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Contact information

Mr Mousa Asiri
Principal investigator, Public, Scientific

Saudi Arabia
Riyadh
11411
Saudi Arabia

ORCID ID	0000-0003-2119-1400
Phone	+966 546668220
Email	Maseri@psmmc.med.sa

Study information

Primary study design	Interventional
Allocation	Randomized controlled trial
Masking	Blinded (masking used)
Control	Placebo
Assignment	Parallel
Purpose	Prevention
Scientific title	Effectiveness of a structured educational intervention on registered nurses’ knowledge, attitudes, and practices toward adherence to pressure injury prevention: a two-arm randomized controlled trial
Study objectives	To assess the efficacy of a structured, evidence-based educational intervention on registered nurses' performance in pressure injury prevention relative to regular education.
Ethics approval(s)	Approved 01/07/2025, Institutional Review Board of Prince Sultan Military Medical City (Saudi Arabia, Riyadh, 11411, Saudi Arabia; +966 546668220; ethical@psmmc.med.sa), ref: E-2601
Health condition(s) or problem(s) studied	Registered nurses’ knowledge, attitudes, and practices toward adherence to pressure injury prevention
Intervention	This study used a parallel-group, two-arm randomized controlled trial (RCT) to assess the efficacy of a structured educational intervention on registered nurses' knowledge, attitudes, and practices (KAP) regarding adherence to pressure injury prevention (Asiri et al., 2025). Nurses who met the eligibility criteria were randomly assigned in a 1:1 ratio to either an intervention group, which received a comprehensive, evidence-based program for pressure injury prevention education, or a control group, which received routine instruction (Houser & Oja, 2025; Potter et al., 2025). Randomization was performed using a computer-generated random sequence, with allocation concealment ensured by sequentially numbered, opaque, sealed envelopes (Clark et al., 2021). Participant blinding was impractical given the characteristics of the educational intervention; however, outcome evaluation and data analysis were conducted using standardized protocols to reduce bias (Melnyk & Morrison-Beedy, 2018). The outcomes were assessed at baseline for the intervention group and weekly for the routine group using validated instruments that evaluated knowledge, attitudes, and practices related to adherence to pressure injury prevention (Melnyk & Morrison-Beedy, 2018). The trial was executed in compliance with Good Clinical Practice standards and is documented in accordance with the CONSORT guidelines for randomized controlled trials (Hopewell et al., 2025).
Intervention type	Other
Primary outcome measure(s)	Nurses’ adherence to pressure injury prevention measured using a validated adherence questionnaire (QARPPU) at baseline and immediately post-intervention
Key secondary outcome measure(s)	Nurses’ knowledge of pressure injury prevention measured using the Pressure Ulcer Knowledge Assessment Tool (PUKAT-2) at baseline and immediately post-intervention Nurses’ self-reported pressure injury prevention practices measured using the Practice questionnaire (Thomas & Nain, 2023) at baseline and immediately post-intervention
Completion date	01/12/2025

Eligibility

Participant type(s)
Age group	Adult
Lower age limit	22 Years
Upper age limit	60 Years
Sex	All
Target sample size at registration	250
Total final enrolment	222
Key inclusion criteria	1. Registered nurses who delivered direct patient care in the participating units 2. Minimum of one year of clinical experience in the nursing department of the same facility 3. Nurses are prepared to grant informed consent
Key exclusion criteria	1. On prolonged leave during the research duration 2. Intended to relocate from the unit during subsequent evaluation 3. Had undergone similar organized pressure injury prevention training during the last six months 4. Did not provide direct care to patients
Date of first enrolment	15/07/2025
Date of final enrolment	15/07/2025

Locations

Countries of recruitment

Saudi Arabia

Study participating centre

Prince Sultan Military Medical City

Saudi Arabia
Riaydh
11411
Saudi Arabia

Results and Publications

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not expected to be made available
IPD sharing plan

Editorial Notes

05/01/2026: Study's existence confirmed by the Institutional Review Board of Prince Sultan Military Medical City.