Prevalence and causes of acute abdominal pain in adult patients presenting to the emergency department in Aleppo university hospital: a cross-sectional study
| ISRCTN | ISRCTN15514055 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN15514055 |
- Submission date
- 01/11/2024
- Registration date
- 04/11/2024
- Last edited
- 04/11/2024
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Signs and Symptoms
Plain English summary of protocol
Background and study aims
This study aims to understand the different causes of sudden abdominal pain in patients who come to the emergency department. We want to find out how common each cause is and how accurate different tests and examinations are in diagnosing these conditions.
Who can participate?
Adults aged 13 years and older who come to the emergency department with sudden abdominal pain can participate in this study. We are not including patients with chronic or unspecified abdominal pain, or those under 13 years old.
What does the study involve?
Participants will be asked to fill out a questionnaire about their symptoms, medical history, and other relevant information. They will also undergo a clinical examination and may have laboratory tests and imaging investigations as part of their routine care. The data collected will help us identify the causes of their abdominal pain and evaluate the accuracy of different diagnostic methods.
What are the possible benefits and risks of participating?
By participating, patients will contribute to improving the understanding and diagnosis of acute abdominal pain, which could benefit future patients. There are no additional risks beyond those associated with the routine medical care they will receive.
Where is the study run from?
Emergency Department of Aleppo University Hospital (Syria)
When is the study starting and how long is it expected to run for?
August 2024 to December 2024
Who is funding the study?
Investigator initiated and funded
Who is the main contact?
Mohammad Al-Jawad, mhammadjawad877@gmail.com
Contact information
Public, Scientific, Principal Investigator
Aleppo University
Aleppo
-
Syria
 ORCID ID |
0009-0002-7633-3541 |
|---|---|
| Phone | +963 946148173 |
| mhammadjawad877@gmail.com |
Study information
| Study design | Single-center cross-sectional observational study |
|---|---|
| Primary study design | Observational |
| Secondary study design | Cross sectional study |
| Study setting(s) | Hospital |
| Study type | Screening |
| Participant information sheet | No participant information sheet available |
| Scientific title | Understanding acute abdominal pain: a study from Aleppo university hospital |
| Study acronym | PACAP |
| Study objectives | To determine the prevalence causes of differential diagnoses for acute abdominal pain in patients presenting to the emergency department. |
| Ethics approval(s) |
Approved 25/08/2024, University of Aleppo Ethics Committee (-, Aleppo, -, Syria; +963 212622301; cmoffice@alepuniv.edu.sy), ref: 2408 |
| Health condition(s) or problem(s) studied | Prevalence and causes of acute abdominal pain in adult patients presenting to the Emergency Department at Aleppo University Hospital |
| Intervention | This study employs a cross-sectional observational methodology. Adult patients presenting with acute abdominal pain at the Emergency Department of Aleppo University Hospital will be assessed. Data will be collected through structured interviews and clinical examinations. Relevant tests, such as blood tests and imaging studies (e.g., ultrasound), will be performed as deemed necessary by the attending physicians. Observations regarding the patients' demographics, clinical presentations, and final diagnoses will be documented to identify the prevalence and causes of acute abdominal pain. |
| Intervention type | Not Specified |
| Primary outcome measure | Measured at a single time point: 1. Prevalence of differential diagnoses for acute abdominal pain is measured using clinical records 2. Most common cause of acute abdominal pain is measured using clinical records 3. Diagnostic accuracy of clinical examination is measured using sensitivity and specificity analysis 4. Diagnostic accuracy of laboratory investigations is measured using sensitivity and specificity analysis 5. Diagnostic accuracy of imaging investigations is measured using sensitivity and specificity analysis 6. Age is measured using a questionnaire 7. Gender is measured using a questionnaire 8. Marital status is measured using a questionnaire 9. Employment status is measured using a questionnaire 10. Location of abdominal pain is measured using a questionnaire 11. Duration of abdominal pain is measured using a questionnaire 12. Nature of abdominal pain is measured using a questionnaire 13. Associated symptoms are measured using a questionnaire 14. Progression of symptoms is measured using a questionnaire 15. Previous treatment for abdominal pain is measured using a questionnaire 16. Abdominal examination findings are measured using clinical examination 17. Radiation of pain is measured using a questionnaire 18. Alleviating or exacerbating factors are measured using a questionnaire 19. Pain score is measured using the NRS scale 20. Impact on daily activities is measured using a questionnaire 21. Significant clinical findings are measured using clinical examination 22. Laboratory test results are measured using laboratory tests 23. Imaging investigation results are measured using imaging tests 24. Final diagnosis is measured using clinical records |
| Secondary outcome measures | There are no secondary outcome measures |
| Overall study start date | 25/08/2024 |
| Completion date | 01/12/2024 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Lower age limit | 13 Years |
| Upper age limit | 100 Years |
| Sex | Both |
| Target number of participants | 900 |
| Total final enrolment | 951 |
| Key inclusion criteria | 1. Adult patients (aged 13 years and above) 2. Patients with acute abdominal pain |
| Key exclusion criteria | 1. Chronic abdominal pain 2. Unspecified abdominal pain 3. Patient under 13 years |
| Date of first enrolment | 01/10/2024 |
| Date of final enrolment | 30/10/2024 |
Locations
Countries of recruitment
- Syria
Study participating centre
-
Syria
Sponsor information
University/education
Aleppo
Aleppo
963
Syria
| Phone | +963 212622301 |
|---|---|
| cmoffice@alepuniv.edu.sy | |
| Website | http://www.alepuniv.com/ |
"ROR" |
https://ror.org/03mzvxz96 |
Funders
Funder type
Other
No information available
Results and Publications
| Intention to publish date | 15/12/2024 |
|---|---|
| Individual participant data (IPD) Intention to share | Yes |
| IPD sharing plan summary | Available on request |
| Publication and dissemination plan | Planned publication in a peer-reviewed journal |
| IPD sharing plan | The datasets generated during and/or analysed during the current study will be available upon request from Mohammad Al-Jawad, mhammadjawad877@gmail.com. |
Editorial Notes
04/11/2024: Study's existence confirmed by the University of Aleppo Ethics Committee.
