Improving quality of referral: a cost-effectiveness evaluation of clinical guidelines for infertility management across the interface

ISRCTN	ISRCTN15571556
DOI	https://doi.org/10.1186/ISRCTN15571556
Protocol serial number	PSI02-09
Sponsor	Record Provided by the NHS R&D 'Time-Limited' National Programme Register - Department of Health (UK)
Funder	NHS Primary and Secondary Care Interface National Research and Development Programme (UK)

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Dr Jill Morrison
Scientific

Department of General Practice
University of Glasgow
4 Lancaster Crescent
Glasgow
G12 0RR
United Kingdom

Phone	+44 (0)141 211 1666
Email	jmm4y@clinmed.gla.ac.uk

Primary study design	Interventional
Study design	Randomised controlled trial
Secondary study design	Randomised controlled trial
Scientific title
Study objectives	How do clinical guidelines affect the management of infertility in general practice? Clinical guidelines were developed locally by consensus and informed by available evidence. Their dissemination included educational meetings.
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Pregnancy and childbirth: Pregnancy
Intervention	The guidelines were evaluated in a cluster randomised controlled trial (RCT). General practices in the intervention arm received the guidelines and those in the control arm were told they would receive them after one year.
Intervention type	Other
Primary outcome measure(s)	1. The time from presentation to referral 2. Investigations completed in general practice 3. Number and content of hospital outpatient visits 4. The time to reach a management plan 5. Costs for referrals from the two groups
Key secondary outcome measure(s)	Not provided at time of registration
Completion date	31/12/2000

Participant type(s)	Patient
Age group	Adult
Sex	All
Target sample size at registration	689
Key inclusion criteria	The sample comprised all general practices in Greater Glasgow Health Board Area (n = 621,at the beginning of the study). All referrals to each of five hospitals in Glasgow managing infertility were collected for one year.
Key exclusion criteria	Not provided at time of registration
Date of first enrolment	01/01/1997
Date of final enrolment	31/12/2000

Department of General Practice

Glasgow
G12 0RR
United Kingdom

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	Results	26/05/2001		Yes	No