Effects of a 24-week block-based versus circuit-based exercise program in overweight and obese Chilean adults

ISRCTN ISRCTN16284357
DOI https://doi.org/10.1186/ISRCTN16284357
Sponsor Universidad Internacional Iberoamericana
Funder Investigator initiated and funded
Submission date
05/07/2026
Registration date
06/07/2026
Last edited
06/07/2026
Recruitment status
Not yet recruiting
Overall study status
Ongoing
Condition category
Nutritional, Metabolic, Endocrine
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year

Plain English summary of protocol

Background and study aims
Overweight and obesity are very common health problems that increase the risk of developing conditions such as diabetes, high blood pressure, and heart disease. Physical exercise is one of the main strategies for improving the health of people with excess body weight. However, it is still unclear which way of organizing resistance training provides the greatest health benefits. This study aims to compare two types of resistance training (block training and circuit training) to evaluate their effects on heart function, body composition, physical activity levels, and quality of life in adults with overweight and obesity.

Who can participate?
Adult men with overweight or obesity who meet the study eligibility criteria and agree to participate voluntarily by providing written informed consent.

What does the study involve?
Participants will be randomly assigned to one of two resistance training programs: block training or circuit training. Both programs will last for 24 weeks and include three supervised exercise sessions per week. Before and after the training program, participants will undergo assessments of body composition, muscle strength, functional capacity, heart rate variability, physical activity level, and quality of life using physical measurements and validated questionnaires.

What are the possible benefits and risks of participating?
Participants may improve their physical fitness, body composition, cardiovascular health, physical activity level, and quality of life. The risks are similar to those of any exercise program and include muscle soreness, fatigue, or minor exercise-related injuries. All training sessions will be supervised by qualified professionals to minimize these risks.

Where is the study run from?
Arturo Prat University (Chile)

When is the study starting and how long is it expected to run for?
The study is expected to begin on 13 July 2026. Each participant will take part in the study for approximately 24 weeks, and the entire project is expected to last approximately 7 months.

Who is funding the study?
This study has no external funding.

Who is the main contact?
Héctor Fuentes Barría, hefuentes_@unap.cl

Contact information

Prof Héctor Fuentes Barría
Principal investigator, Scientific, Public

2120 Arturo Prat Avenue
Iquique
1110939
Chile

ORCiD logoORCID ID 0000-0003-0774-0848
Phone +56 (0)9996702455
Email hefuentes_@unap.cl

Study information

Primary study designInterventional
AllocationRandomized controlled trial
MaskingBlinded (masking used)
ControlActive
AssignmentParallel
PurposePrevention, Treatment
Scientific titleEffects of a 24-week block-based versus circuit-based exercise program in overweight and obese Chilean adults
Study objectives To evaluate the effects of a block based physical exercise program versus a circuit exercise program both individualized based on heart rate variability on cardiovascular autonomic regulation, body composition, and quality of life in overweight and obese Chilean adults.
Ethics approval(s)

Approved 03/07/2026, Ethics Committee of the Iberoamerican International University (Calle 15 No. 36, between 10 and 12, Campeche, 24560, Mexico; +56 (0)(981) 811 0246; contacto@unini.edu.mx), ref: CR-252

Health condition(s) or problem(s) studiedCardiovascular autonomic regulation, body composition, and quality of life in Chilean adults with overweight and obesity
InterventionThe study involved a 24-week resistance training program with three weekly sessions (Monday, Wednesday, and Friday), each lasting 48 to 57 minutes. Participants were randomly assigned to either an experimental group (EG) or a control group (CG) using a stratified 1:1 allocation method to ensure unbiased group distribution.

The EG performed resistance exercises in blocks (push-ups, mountain climbers, squats, jumping jacks, burpees, and skipping), while the CG performed the same exercises in a circuit format. Training intensity was monitored using Polar® devices, and total training volume was equivalent in both groups, with differences only in exercise distribution. The program was structured into a warm-up (5 min), main phase (38–47 min), and cool-down (5 min). Heart rate was targeted at 60–90% of maximum heart rate throughout the 24 weeks, with adjustments based on Karvonen’s formula. Both groups followed a fixed rest schedule between repetitions and sets.

Assessments were conducted before and after the intervention to evaluate physical activity level, body composition, muscle strength, functional capacity, sprint performance, recovery, and quality of life.
Intervention typeBehavioural
Primary outcome measure(s)
  1. Body composition measured using Metabolic Equivalent of Task, Body Mass Index and waist circumference at 24 weeks
Key secondary outcome measure(s)
  1. Muscle strength measured using right and left hand grip dynamometer at 24 weeks
  2. Speed measured using running anaerobic sprint test at 24 weeks
  3. Functional capacity measured using 6-minute walking test at 24 weeks
  4. Recovery capacity measured using heart rate variability in the Low Frequency/High Frequency (LF/HF) ratio and Root Mean Square of Successive Differences (RMSSD) at 24 weeks
  5. Physical activity level measured using the International Physical Activity Questionnaire – Short Form (IPAQ-SF) at 24 weeks
  6. Quality of life measured using the World Health Organization Quality of Life Instrument – Brief version (WHOQOL-BREF) at 24 weeks
Completion date27/12/2026

Eligibility

Participant type(s)
Age groupAdult
Lower age limit18 Years
Upper age limit44 Years
SexMale
Target sample size at registration52
Total final enrolment52
Key inclusion criteria1. Chilean adults aged 18 to 44 classified as overweight or obese based on body mass index
2. Participants must refrain from moderate- or vigorous-intensity physical activity for the 48 hours prior to each assessment or training session to avoid interfering with the acute physiological response
3. Punctual and regular attendance at all scheduled training sessions throughout the 24-week intervention
4. Sign an informed consent form
5. Proper understanding of the study's procedures, objectives, and potential risks
Key exclusion criteria1. Significant metabolic diseases or musculoskeletal conditions that limit physical exercise
2. Perform below 644 m on the 6-minute walk test
3. Simultaneously participating in another physical training program during the intervention period.
Date of first enrolment10/07/2026
Date of final enrolment12/07/2026

Locations

Countries of recruitment

  • Chile

Study participating centres

Results and Publications

Individual participant data (IPD) Intention to shareNo

Editorial Notes

06/07/2026: Study's existence confirmed by the Ethics Committee of the Iberoamerican International University.