Mesothelioma - Early versus Delayed Chemotherapy

ISRCTN	ISRCTN16586512
DOI	https://doi.org/10.1186/ISRCTN16586512
Protocol serial number	MED
Sponsor	The Royal Marsden NHS Foundation Trust (UK)
Funder	Royal Marsden Hospital (UK)

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Dr - -
Scientific

UKCCCR Register Co-ordinator
MRC Clinical Trials Unit
222 Euston Road
London
NW1 2DA
United Kingdom

Primary study design	Interventional
Study design	Randomised controlled trial
Secondary study design	Randomised controlled trial
Study type	Participant information sheet
Scientific title
Study objectives	Not provided at time of registration
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Mesothelioma
Intervention	1. Best supportive care + chemotherapy at presentation versus 2. Best supportive care + chemotherapy when symptoms progress
Intervention type	Other
Primary outcome measure(s)	Not provided at time of registration
Key secondary outcome measure(s)	Not provided at time of registration
Completion date	31/12/2003

Participant type(s)	Patient
Age group	Adult
Lower age limit	18 Years
Sex	Not Specified
Target sample size at registration	43
Key inclusion criteria	1. Patients with histologically verified malignant mesothelioma - Performance status (PS) 0-2 - Asymptomatic or stable symptoms 2. Age at least 18 years
Key exclusion criteria	Not provided at time of registration
Date of first enrolment	01/08/1999
Date of final enrolment	31/12/2003

UKCCCR Register Co-ordinator

London
NW1 2DA
United Kingdom

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	01/02/2006		Yes	No
Participant information sheet	Participant information sheet	11/11/2025	11/11/2025	No	Yes