Telephone-administered cognitive behaviour therapy (CBT) for the treatment of obsessive compulsive disorder: A randomized controlled trial

ISRCTN	ISRCTN16800815
DOI	https://doi.org/10.1186/ISRCTN16800815
Protocol serial number	RDO/28/1/26
Sponsor	North West Research and Development Support Unit (UK)
Funder	North West Research and Development Support Unit, Salford (Ref: RDO/28/1/26) - regional NHS R&D funding stream

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Prof Karina Lovell
Scientific

School of Nursing
Midwifery & Social Work
The University of Manchester
Oxford Road
Manchester
M13 9PL
United Kingdom

Primary study design	Interventional
Study design	Randomised controlled trial
Secondary study design	Randomised controlled trial
Scientific title	Telephone-administered cognitive behaviour therapy (CBT) for the treatment of obsessive compulsive disorder: A randomized controlled trial
Study objectives	Exposure therapy and response prevention will yield equivalent clinical outcomes whether delivered by telephone or by face to face therapist contact in the treatment of obsessive-compulsive disorder
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Obsessive-compulsive disorder (OCD)
Intervention	Exposure therapy and response prevention delivered by either telephone or face to face
Intervention type	Behavioural
Primary outcome measure(s)	CBT delivered by telephone shows equivalent clinical outcome as face to face therapy and similar levels of satisfaction were reported.
Key secondary outcome measure(s)	Cost-minimisation analysis shows that treatment by telephone is cheaper than face to face CBT. The main cost-driver is treatment time defined by the protocol and, for telephone-administered CBT, this duration was shorter.
Completion date	30/09/2002

Participant type(s)	Patient
Age group	Adult
Lower age limit	16 Years
Upper age limit	65 Years
Sex	All
Target sample size at registration	80
Total final enrolment	72
Key inclusion criteria	1. Obsessive-compulsive disorder as the main presenting problem 2. Meet Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria for OCD 3. Yale-Brown Obsessive Compulsive Scale (Y-BOCS) score of 16 and over 4. Aged between 16-65 5. Agree to, and give written consent to participate in the study
Key exclusion criteria	1. Obsessions without overt compulsions 2. Obsessional slowness 3. Organic brain disease 4. On a stable dose of antidepressants or anxiolytic medication for less than 3 months 5. Past or present psychosis 6. Meet DSM-IV criteria for substance abuse or dependence 7. Currently on more than 10 mg of Diazepam or equivalent daily 8. Severe depression >30 on Beck Depression Inventory (BDI) 9. Suicidal intent
Date of first enrolment	01/10/2000
Date of final enrolment	30/09/2002

School of Nursing

Manchester
M13 9PL
United Kingdom

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan	Not provided at time of registration

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article		28/10/2006		Yes	No

08/11/2022: Internal review.