STroke inpatient secOndary Prevention: current status and continuous care improvement

ISRCTN	ISRCTN17207064
DOI	https://doi.org/10.1186/ISRCTN17207064
Protocol serial number	1
Sponsor	Beijing Tiantan Hospital (China)
Funder	Beijing Municipal Science & Technology Commission (China)

Submission date: 30/03/2007
Registration date: 26/04/2007
Last edited: 22/09/2021

Recruitment status: No longer recruiting
Overall study status: Completed
Condition category: Circulatory System

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Contact information

Prof Wang Yongjun
Scientific

Beijing Tiantan Hospital
Tiantan Xili 6
Chongwen District
Beijing
100050
China

Email	yongjunw@hotmail.com

Study information

Primary study design	Observational
Study design	The trial is a prospective cohort study. Because the staff take turns to care for the patients in different wards, it is impossible to randomise grouping.
Secondary study design	Cohort study
Scientific title	STroke inpatient secOndary Prevention: current status and continuous care improvement
Study acronym	STOP
Study objectives	The secondary prevention collaborative system is hospitalised; for doctors, it can increase the coincidence with the therapeutic regime and for patients, it can improve the compliance to the risk factor controls.
Ethics approval(s)	Approval gained from the Beijing Tiantan Hospital Capital Medical University Ethics Board on the January 19, 2007.
Health condition(s) or problem(s) studied	Ischaemic stroke and Transient Ischaemic Attack (TIA)
Intervention	The conception of this project is to organise the effective stroke secondary prevention program, which is initiated at hospitalisation, into the whole course of stroke care, thus improving the prophylaxis of inpatients with ischaemic stroke or TIA, on medical compliance, confidence, preventive efficacy. There are three treatments: 1. The medical treatment includes drug treatments of hypertension, dyslipoidemia, carotid stenosis, and anti-platelet agents 2. The surgical treatment includes carotid endarterctomy, carotid angioplasty and stent 3. Lifestyle modifications comprise of stopping smoking, weight control and public education The program is practiced on all patients who have a probability of scleratheromic stroke.
Intervention type	Other
Primary outcome measure(s)	1. The coincidence with the therapeutic regimen 2. The compliance to the risk factor controls
Key secondary outcome measure(s)	The reoccurrence rate of vascular issues.
Completion date	01/06/2008

Eligibility

Participant type(s)	Patient
Age group	Not Specified
Sex	Not Specified
Target sample size at registration	1600
Key inclusion criteria	1. Age equal to or older than 18 years 2. Ischaemic event (infarction/Transient Ischaemic Attack [TIA]) within two weeks 3. Diagnosis of infarction or TIA Infarction: a. sudden or rapid onset of focal ischaemic neurological impairments by all kinds of reasons b. the impairments last more than 24 hours TIA: a. sudden or rapid onset of focal ischaemic neurological impairments by all kinds of reasons b. the impairments are within 24 hours (the diagnosis could be made if the patient have one of the symptoms: amaurosis fugax, dysphasia, movement disorder such as weakness or clumsiness; but such symptoms as diplopia, scintillation, scotosis, vertigo, memory disorder and ataxia cannot support the diagnoses; the symptoms that may be caused by migraine are ruled out) 4. No matter which one it is, all have either a Computed Tomography (CT) or a Magnetic Resonance Imaging (MRI) scan, to preclude haemorrhage or other non-ischaemic nerve system diseases 5. All the diagnoses have been confirmed and registered by the research centre neurologist 6. Patient resident in Beijing for at least one year 7. Patient consents to follow up for at least one year 8. Mechanism of the event is probably infarction/TIA due to artery scleratheroma 9. More than one modifiable risk factors of Cardiovascular Disease (CVD) 10. The case collected in each research centre should be consecutive. Even the patients who qualified but reject to join in, should also be added in the sum and registered with the basic items such as name, sex, age
Key exclusion criteria	1. Pregnancy 2. Silent infarction without symptoms or focal signs 3. Venous infarction 4. Other causes of ischaemic stroke but not scleratheromic. For example, cardiac resource, hyper-coagulation, dissection, vasculitis, medical resource such as the complications of carotid endarterctomy or angiography, traumatic resource, aura migraine, epilepsy, other non-ischaemic stroke 5. Reject to join in the study 6. Event episode concomitant with cardiac disease, cardiac insufficiency, hepatosis, renal inadequacy, respiratory failure, malignant tumour etc., and anticipate not to accomplish the one year-follow up 7. Glasgow Coma Score (GCS) less than four
Date of first enrolment	01/10/2006
Date of final enrolment	01/06/2008

Locations

Countries of recruitment

China

Study participating centre

Beijing Tiantan Hospital

Beijing
100050
China

Results and Publications

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan

Editorial Notes

22/09/2021: Proactive update review. No publications found. Search options exhausted.