A prospective randomised, double-blind controlled trial of intravenous aminophylline versus placebo in patients with acute exacerbations of COPD
| ISRCTN | ISRCTN17312089 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN17312089 |
| Secondary identifying numbers | N0025107117 |
- Submission date
- 12/09/2003
- Registration date
- 12/09/2003
- Last edited
- 08/01/2009
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Respiratory
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr Paul Walker
Scientific
Scientific
Chest Unit
3rd Floor Clinical Science Building
University Hospital Aintree
Longmoor Lane
Liverpool
L9 7AL
United Kingdom
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Not specified |
| Study type | Not Specified |
| Scientific title | |
| Study objectives | Whether intravenous aminophylline provides any benefit to patients with acute exacerbations of COPD. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Respiratory: Chronic obstructive pulmonary disease (COPD) |
| Intervention | Intravenous aminophylline vs placebo |
| Intervention type | Other |
| Primary outcome measure | Not provided at time of registration |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/02/2002 |
| Completion date | 01/02/2005 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Not Specified |
| Target number of participants | 40 controls and 40 COPD patients |
| Key inclusion criteria | 80 adult subjects aged 40-80 years. |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/02/2002 |
| Date of final enrolment | 01/02/2005 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
Chest Unit
Liverpool
L9 7AL
United Kingdom
L9 7AL
United Kingdom
Sponsor information
Department of Health (UK)
Government
Government
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Website | http://www.doh.gov.uk |
|---|
Funders
Funder type
Government
Aintree Hospitals NHS Trust (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/09/2005 | Yes | No |
