Adrenaline Usage to Reduce Blood Transfusions Following Hip Fracture Surgery: A Randomised Clinical Study.
| ISRCTN | ISRCTN17472370 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN17472370 |
| Protocol serial number | N0265041838 |
| Sponsor | Department of Health |
| Funder | University Hospital Birmingham NHS Trust (UK) |
- Submission date
- 30/09/2005
- Registration date
- 30/09/2005
- Last edited
- 14/03/2014
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Surgery
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Mr D Clark
Scientific
Scientific
Trauma
Selly Oak Hospital
Birmingham
B29 6JD
United Kingdom
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | Our hypothesis is that by using intraoperative swabs soaked in an adrenaline solution we will decrease surgical blood loss and hence decrease the need for postoperative and intraoperative blood transfusion. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Surgery: Hip fracture |
| Intervention | Randomly allocated to two groups (32 patients per group): Group A: Wound site infiltrated with 10mls 0.5% marcain with adrenaline. Group B: All swabs used intraoperatively soaked in a solution made up of 5 mg of adrenaline in 1 litre N/Saline. |
| Intervention type | Drug |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | Adrenaline |
| Primary outcome measure(s) |
Measured reduction in postoperative and interoperative blood loss. |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/01/2007 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target sample size at registration | 64 |
| Key inclusion criteria | Patients with fracture of the proximal femur requiring Dynamic Hip Screw fixation. |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/01/2004 |
| Date of final enrolment | 01/01/2007 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Trauma
Birmingham
B29 6JD
United Kingdom
B29 6JD
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
