Adrenaline Usage to Reduce Blood Transfusions Following Hip Fracture Surgery: A Randomised Clinical Study.
| ISRCTN | ISRCTN17472370 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN17472370 |
| Secondary identifying numbers | N0265041838 |
- Submission date
- 30/09/2005
- Registration date
- 30/09/2005
- Last edited
- 14/03/2014
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Surgery
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Mr D Clark
Scientific
Scientific
Trauma
Selly Oak Hospital
Birmingham
B29 6JD
United Kingdom
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Not Specified |
| Scientific title | |
| Study objectives | Our hypothesis is that by using intraoperative swabs soaked in an adrenaline solution we will decrease surgical blood loss and hence decrease the need for postoperative and intraoperative blood transfusion. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Surgery: Hip fracture |
| Intervention | Randomly allocated to two groups (32 patients per group): Group A: Wound site infiltrated with 10mls 0.5% marcain with adrenaline. Group B: All swabs used intraoperatively soaked in a solution made up of 5 mg of adrenaline in 1 litre N/Saline. |
| Intervention type | Drug |
| Pharmaceutical study type(s) | |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | Adrenaline |
| Primary outcome measure | Measured reduction in postoperative and interoperative blood loss. |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/01/2004 |
| Completion date | 01/01/2007 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target number of participants | 64 |
| Key inclusion criteria | Patients with fracture of the proximal femur requiring Dynamic Hip Screw fixation. |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/01/2004 |
| Date of final enrolment | 01/01/2007 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
Trauma
Birmingham
B29 6JD
United Kingdom
B29 6JD
United Kingdom
Sponsor information
Department of Health
Government
Government
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Phone | +44 (0)20 7307 2622 |
|---|---|
| dhmail@doh.gsi.org.uk | |
| Website | http://www.dh.gov.uk/Home/fs/en |
Funders
Funder type
Government
University Hospital Birmingham NHS Trust (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
