A randomised placebo controlled trial to examine the effect and onset of action of dutasteride on the expression of vascular endothelial growth factor and microvessel density
| ISRCTN | ISRCTN18102429 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN18102429 |
| Protocol serial number | N0116131095 |
| Sponsor | Department of Health |
| Funder | Kings College Hospital NHS Trust R&D Consortium (UK) |
- Submission date
- 30/09/2004
- Registration date
- 30/09/2004
- Last edited
- 26/01/2016
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Surgery
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Mr Gordon Muir
Scientific
Scientific
Department of Urology
King's College Hospital
Denmark Hill
London
SE5 9RS
United Kingdom
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Study type | Participant information sheet |
| Scientific title | A randomised placebo controlled trial to examine the effect and onset of action of dutasteride on the expression of vascular endothelial growth factor and microvessel density |
| Study objectives | Not provided at time of registration |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Surgery: Prostatectomy |
| Intervention | Randomised to dutasteride or placebo prior to surgery. |
| Intervention type | Drug |
| Phase | Not Applicable |
| Drug / device / biological / vaccine name(s) | Dutasteride |
| Primary outcome measure(s) |
Not provided at time of registration |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/01/2004 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Male |
| Key inclusion criteria | Not provided at time of registration |
| Key exclusion criteria | Does not meet inclusion criteria |
| Date of first enrolment | 01/06/2003 |
| Date of final enrolment | 01/01/2004 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
King's College Hospital
London
SE5 9RS
United Kingdom
SE5 9RS
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Participant information sheet | Participant information sheet | 11/11/2025 | 11/11/2025 | No | Yes |
Editorial Notes
26/01/2016: no publications found on PubMed.
