An evaluation of systemic metronidazole and amoxycillin as an adjunct to routine therapy in the treatment of severe periodontal disease
| ISRCTN | ISRCTN18247441 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN18247441 |
| Protocol serial number | R/ROONEY/291 |
| Sponsor | NHS R&D Regional Programme Register - Department of Health (UK) |
| Funder | NHS Executive South West (UK) |
- Submission date
- 23/01/2004
- Registration date
- 23/01/2004
- Last edited
- 06/01/2010
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Oral Health
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Mrs Jane Rooney
Scientific
Scientific
University of Bristol
Dental Hospital and School
Lower Maudlin Street
Bristol
BS1 2LY
United Kingdom
| Phone | +44 (0)117 9294472 |
|---|---|
| J.C.Rooney@bristol.ac.uk |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | The aim of this study is to evaluate systematic metronidazole and amoxycillin, alone and combined, as adjuncts to root planning in the treatment of patients with severe adult periodontis. In addition, microbiological monitoring will be performed in order to determine of pre-treatment microbiological status influences treatment outcome. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Oral health/stomatognathic diseases: Severe periodontal disease |
| Intervention | Not provided at time of registration |
| Intervention type | Drug |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | metronidazole and amoxycillin |
| Primary outcome measure(s) |
Not provided at time of registration |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/06/1997 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Not Specified |
| Target sample size at registration | 66 |
| Key inclusion criteria | Not provided at time of registration |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/06/1994 |
| Date of final enrolment | 01/06/1997 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
University of Bristol
Bristol
BS1 2LY
United Kingdom
BS1 2LY
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/04/2002 | Yes | No |
