A randomised double-blind placebo-controlled study to investigate the possible role of Opiate Morphine (MST) in the treatment of chronic cough.
| ISRCTN | ISRCTN18474014 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN18474014 |
| Protocol serial number | N0084139674 |
| Sponsor | Department of Health |
| Funder | The North and South Bank Research and Development Consortium (UK) |
- Submission date
- 30/09/2004
- Registration date
- 30/09/2004
- Last edited
- 22/09/2009
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Respiratory
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Miss Caroline Wright
Scientific
Scientific
Academic Department of Medicine
Castle Hill Hospital
Castle Road
Cottingham
HU16 5JQ
United Kingdom
| Phone | +44 (0)1482 875875 (4009/3782) |
|---|---|
| c.e.wright@hull.ac.uk |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised double blind placebo controlled parallel group trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | To evaluate whether administration of opiates in the form of morphine produces a reduction in cough frequency and severity in patients with previously unsuccessfully treated cough. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Chronic cough |
| Intervention | A randomised double-blind placebo-controlled study |
| Intervention type | Other |
| Primary outcome measure(s) |
Not provided at time of registration |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 31/03/2005 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target sample size at registration | 30 |
| Key inclusion criteria | 30 subjects from Hull Cough Clinic |
| Key exclusion criteria | Does not match inclusion criteria |
| Date of first enrolment | 16/12/2003 |
| Date of final enrolment | 31/03/2005 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Academic Department of Medicine
Cottingham
HU16 5JQ
United Kingdom
HU16 5JQ
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 15/02/2007 | Yes | No |
