Patient or carer acceptance of medicine use recommendations by a pharmacist after being discharged from hospital
| ISRCTN | ISRCTN21156862 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN21156862 |
| ClinicalTrials.gov number | Nil Known |
- Submission date
- 10/07/2022
- Registration date
- 12/07/2022
- Last edited
- 30/03/2023
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Injury, Occupational Diseases, Poisoning
Plain English Summary
Background and study aims
Inappropriate use of medicines is common, and patients benefit from having their medicines reviewed by an independent third party who is skilled at reviewing medicines. This study aims to explain to patients leaving the hospital, both verbally and in writing, about any issues that an independent third party have with their medicines. Patients will then be encouraged to discuss these issues with their primary physician.
Who can participate?
Patients in hospital aged 65 years or older
What does the study involve?
The study involves interviewing participants just before they leave the hospital, preferably in the company of a caregiver, to discuss any issues with their medicines. These discussions will be in plain English, and any recommendations will be made both verbally and in writing. The study team asks that participants make an appointment with their doctor within 2 weeks of leaving the hospital to discuss those issues that concern them. The study team will then contact participants by telephone or visit them to find out the results of the recommendations.
What are the possible benefits and risks of participating?
Possible benefits are a correction to the use of inappropriate medicines and a reduction in the number of medicines participants take. The study team is unaware of any risks.
Where is the study run from?
The University of Sydney (Australia)
When is the study starting and how long will it run for?
From July 2019 until March 2020
Who is funding the study?
Wolper Jewish Hospital (Australia)
Who is the main contact?
The hospital's clinical pharmacist, who will attach a professional card to the participant's medication list detailing their name and phone number.
Contact information
Principal Investigator
801/306 Oxford St
Bondi Junction
Sydney
2022
Australia
 ORCID ID |
0000-0002-7125-4492 |
|---|---|
| Phone | +61412852828 |
| ben.basger@sydney.edu.au |
Study information
| Study design | Single centre observational longitudinal cohort study |
|---|---|
| Primary study design | Observational |
| Secondary study design | Cohort study |
| Study setting(s) | Hospital |
| Study type | Quality of life |
| Participant information sheet | 42040_PIS_carers_v1_10Feb19.pdf |
| Scientific title | Uptake of pharmacist recommendations by patients after discharge: Implementation study of a patient-centred medicines review service |
| Study hypothesis | If patients and/or their carers receive medicine management recommendations in ways that are meaningful to them, they are capable of making an informed decision about the recommendation and actioning it. |
| Ethics approval(s) | Approved 17/05/2019, The University of Sydney Human Research Ethics Committee (The University of Sydney, Sydney, NSW, Australia 2005; +61 2 9036 9161; human.ethics@sydney.edu.au), ref: 2019/209 |
| Condition | Identification, resolution, and prevention of medicine-related problems in older people |
| Intervention | Inpatients, and their carers where there was cognitive impairment, were recruited to receive a medicines review upon discharge from the hospital. Medicine management recommendations were delivered verbally and in writing in ways that were meaningful to them. Two to four weeks after discharge, they were followed up to record the implementation rate of the recommendations, accomplished through contact with their primary physician for prescription medicines, or by themselves for non-prescription medicines |
| Intervention type | Behavioural |
| Primary outcome measure | Implementation rate of medicine management recommendations measured using interviews with participants at 2-4 weeks |
| Secondary outcome measures | The number of medicines deprescribed (either reduced in dose or ceased) measured using interviews with participants at 2-4 weeks |
| Overall study start date | 01/03/2019 |
| Overall study end date | 01/07/2020 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Senior |
| Sex | Both |
| Target number of participants | 100 |
| Total final enrolment | 100 |
| Participant inclusion criteria | 1. Inpatients, and a carer for individuals where there is cognitive impairment 2. Aged ≥65 years |
| Participant exclusion criteria | Does not meet inclusion criteria. |
| Recruitment start date | 01/07/2019 |
| Recruitment end date | 01/04/2020 |
Locations
Countries of recruitment
- Australia
Study participating centre
Woollahra
Sydney
2025
Australia
Sponsor information
University/education
The University of Sydney
Camperdown
Sydney
2006
Australia
| Phone | +61 2 8627 8111 |
|---|---|
| human.ethics@sydney.edu.au | |
| Website | www.sydney.edu.au |
"ROR" |
https://ror.org/0384j8v12 |
Funders
Funder type
Hospital/treatment centre
No information available
Results and Publications
| Intention to publish date | 10/10/2022 |
|---|---|
| Individual participant data (IPD) Intention to share | Yes |
| IPD sharing plan summary | Stored in non-publicly available repository, Available on request |
| Publication and dissemination plan | A research manuscript will be submitted to BMC Geriatrics for review and consideration for publication. |
| IPD sharing plan | Current participant level data sharing statement as of 24/01/2023: Raw data is available upon request from Dr Ben Basger at ben.basger@sydney.edu.au. Raw data consists of an Excel spreadsheet containing deidentified patient gender, age, number of medicines taken, and category of Drug Related Problem identified. Data collection forms and patient consent forms are being held securely in the medical records department of the hospital. Previous participant level data sharing statement: Raw data is available upon request from ben.basger@sydney.edu.au. Data collection forms and patient consent forms are being held securely in the medical records department of the hospital. |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Participant information sheet | information for carers version 1 |
01/02/2019 | 12/07/2022 | No | Yes |
| Participant information sheet | information for participants version 1 |
10/01/2019 | 12/07/2022 | No | Yes |
| Results article | 29/03/2023 | 30/03/2023 | Yes | No |
Additional files
- 42040_PIS_patients_v1_10Jan19.pdf
- information for participants
- 42040_PIS_carers_v1_10Feb19.pdf
- information for carers
Editorial Notes
30/03/2023: Publication reference added.
24/01/2023: The participant level data sharing statement was updated.
12/07/2022: Trial’s existence confirmed by Wolper Jewish Hospital.
