Dental plaque control to reduce ventilator-associated pneumonia

ISRCTN ISRCTN21526533
DOI https://doi.org/10.1186/ISRCTN21526533
Secondary identifying numbers N0263177828
Submission date
29/09/2006
Registration date
29/09/2006
Last edited
17/08/2018
Recruitment status
No longer recruiting
Overall study status
Completed
Condition category
Oral Health
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Dr IG Needleman
Scientific

International Centre for Evidence-Based Oral Health
Department of Periodontology
UCL Eastman Dental Institute
256 Grays Inn Road
London
WC1X 8LD
United Kingdom

Phone +44 (0)20 7915 2340
Email I.Needleman@eastman.ucl.ac.uk

Study information

Study designRandomised controlled trial
Primary study designInterventional
Secondary study designRandomised controlled trial
Study setting(s)Not specified
Study typePrevention
Participant information sheet Not available in web format, please use the contact details below to request a patient information sheet
Scientific titleDental plaque control to reduce ventilator-associated pneumonia
Study objectivesDoes a sponge toothette or electric toothbrush differentially affect the oral flora of intubated intensive care patients?
Ethics approval(s)Added 15 May 2008: Joint UCL/UCLH Committee on the Ethics of Human Research, 05/Q0502/135
Health condition(s) or problem(s) studiedOral Health
Intervention1. Sponge toothette
2. Electric toothbrush
Intervention typeOther
Primary outcome measureDescription of extent of dental plaque and bacterial species present in dental plaque of intubated intensive care patients.
Secondary outcome measuresAdded 15 May 2008:
1. Incidence of ventilator associated pneumonia
2. Mortality
Overall study start date01/06/2006
Completion date01/06/2009

Eligibility

Participant type(s)Patient
Age groupNot Specified
SexNot Specified
Target number of participants100 patients from Neurosurgery/NSITU
Key inclusion criteriaAdded 15 May 2008:
Emergency admission to neurosurgical ICU who have:
1. Been in hospital for less than 24 hours prior to their admission to ICU
2. Expected to survive for more than 48 hours
3. Expected to be intubated for at least 48 hours
Key exclusion criteriaAdded 15 May 2008:
1. Edentulous patients
2. Those with a known adverse reaction to chlorhexidine
3. Patients will also be barred who have had a recent chest infection
Date of first enrolment01/06/2006
Date of final enrolment01/06/2009

Locations

Countries of recruitment

  • England
  • United Kingdom

Study participating centre

International Centre for Evidence-Based Oral Health
London
WC1X 8LD
United Kingdom

Sponsor information

Record Provided by the NHSTCT Register - 2006 Update - Department of Health
Government

The Department of Health, Richmond House, 79 Whitehall
London
SW1A 2NL
United Kingdom

Phone +44 (0)20 7307 2622
Email dhmail@doh.gsi.org.uk
Website http://www.dh.gov.uk/Home/fs/en

Funders

Funder type

Government

University College London Hospitals NHS Foundation Trust (UK)

No information available

NHS R&D Support Funding

No information available

Results and Publications

Intention to publish date
Individual participant data (IPD) Intention to shareNo
IPD sharing plan summaryNot provided at time of registration
Publication and dissemination planNot provided at time of registration
IPD sharing plan

Study outputs

Output type Details Date created Date added Peer reviewed? Patient-facing?
Results article results 01/03/2011 Yes No

Editorial Notes

17/08/2018: Publication reference added