Dental plaque control to reduce ventilator-associated pneumonia
| ISRCTN | ISRCTN21526533 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN21526533 |
| Protocol serial number | N0263177828 |
| Sponsor | Record Provided by the NHSTCT Register - 2006 Update - Department of Health |
| Funders | University College London Hospitals NHS Foundation Trust (UK), NHS R&D Support Funding |
- Submission date
- 29/09/2006
- Registration date
- 29/09/2006
- Last edited
- 17/08/2018
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Oral Health
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr IG Needleman
Scientific
Scientific
International Centre for Evidence-Based Oral Health
Department of Periodontology
UCL Eastman Dental Institute
256 Grays Inn Road
London
WC1X 8LD
United Kingdom
| Phone | +44 (0)20 7915 2340 |
|---|---|
| I.Needleman@eastman.ucl.ac.uk |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Study type | Participant information sheet |
| Scientific title | Dental plaque control to reduce ventilator-associated pneumonia |
| Study objectives | Does a sponge toothette or electric toothbrush differentially affect the oral flora of intubated intensive care patients? |
| Ethics approval(s) | Added 15 May 2008: Joint UCL/UCLH Committee on the Ethics of Human Research, 05/Q0502/135 |
| Health condition(s) or problem(s) studied | Oral Health |
| Intervention | 1. Sponge toothette 2. Electric toothbrush |
| Intervention type | Other |
| Primary outcome measure(s) |
Description of extent of dental plaque and bacterial species present in dental plaque of intubated intensive care patients. |
| Key secondary outcome measure(s) |
Added 15 May 2008: |
| Completion date | 01/06/2009 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target sample size at registration | 100 |
| Key inclusion criteria | Added 15 May 2008: Emergency admission to neurosurgical ICU who have: 1. Been in hospital for less than 24 hours prior to their admission to ICU 2. Expected to survive for more than 48 hours 3. Expected to be intubated for at least 48 hours |
| Key exclusion criteria | Added 15 May 2008: 1. Edentulous patients 2. Those with a known adverse reaction to chlorhexidine 3. Patients will also be barred who have had a recent chest infection |
| Date of first enrolment | 01/06/2006 |
| Date of final enrolment | 01/06/2009 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
International Centre for Evidence-Based Oral Health
London
WC1X 8LD
United Kingdom
WC1X 8LD
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/03/2011 | Yes | No | |
| Participant information sheet | Participant information sheet | 11/11/2025 | 11/11/2025 | No | Yes |
Editorial Notes
17/08/2018: Publication reference added
