Test of the open artery hypothesis
| ISRCTN | ISRCTN21931925 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN21931925 |
| Protocol serial number | PG/97051 |
| Sponsor | British Heart Foundation (UK) |
| Funder | British Heart Foundation (UK) (ref: PG/97051) |
- Submission date
- 31/10/2001
- Registration date
- 31/10/2001
- Last edited
- 02/10/2007
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Circulatory System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr MS Marber
Scientific
Scientific
Dept of Cardiology
The Rayne Institute
St Thomas' Hospital
Lambeth Palace Road
London
SE1 7EH
United Kingdom
| Phone | +44 (0)20 7836 5454 |
|---|---|
| mike.marber@kcl.ac.uk |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | Effect on ventricular modelling of angioplasty and stenting of the occluded infarct related artery (IRA) among patients with their first Q wave anterior myocardial infarction. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Cardiovascular disease |
| Intervention | Angiography and angioplasty carried out within 28 days of the acute event. Patients to be randomised into intervention or non-intervention groups. Patients with TIMI grade II or III in the IRA or multi-vessel disease will be excluded. Remaining patients with TIMI grade 0 or I will be randomised to intervention plus optimal medical therapy or optimal medical therapy alone. |
| Intervention type | Other |
| Primary outcome measure(s) |
Not provided at time of registration |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/06/1999 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Key inclusion criteria | Patients with Thrombolysis in Myocardial Infarction (TIMI) grade 0 or I. |
| Key exclusion criteria | Patients with TIMI grade II or III in the IRA or multi-vessel disease will be excluded. |
| Date of first enrolment | 01/03/1997 |
| Date of final enrolment | 01/06/1999 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Dept of Cardiology
London
SE1 7EH
United Kingdom
SE1 7EH
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | Results | 04/09/2002 | Yes | No |
