Nasal decongestant study: a prospective double-blind randomised comparative study of nasal decongestant and vasoconstrictive efficacy of two commonly used preparations, namely cocaine and adrenaline, with normal saline and adrenaline with normal saline
| ISRCTN | ISRCTN24006995 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN24006995 |
| Protocol serial number | N0247184156 |
| Sponsor | Record Provided by the NHSTCT Register - 2007 Update - Department of Health |
| Funder | Swindon and Marlborough NHS Trust (UK) |
- Submission date
- 28/09/2007
- Registration date
- 28/09/2007
- Last edited
- 05/06/2014
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Surgery
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Mr Deepak Gupta
Scientific
Scientific
Swindon & Marlborough NHS Trust
The Great Western Hospital
Marlborough Road
Swindon
SN3 6BB
United Kingdom
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | During endoscopic nasal surgery a pre-operative topical decongestion of the nose is achieved in the theatre by instillation of a decongestant solution. During operation this solution is used to achieve haemostasis. This research aims to compare the efficacy of two preparations and justify the use of cocaine. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Surgery: Nose |
| Intervention | Cocaine and adrenaline with normal saline and adrenaline with normal saline |
| Intervention type | Drug |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | Cocaine, adrenaline, normal saline |
| Primary outcome measure(s) |
Not provided at time of registration |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/11/2006 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Key inclusion criteria | Not provided at time of registration |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/08/2006 |
| Date of final enrolment | 01/11/2006 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Swindon & Marlborough NHS Trust
Swindon
SN3 6BB
United Kingdom
SN3 6BB
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
