Total value of intensive exercise training (three weeks) immediately after hospital discharge for arthritis patients due to a flare of disease activity or for elective joint replacements
| ISRCTN | ISRCTN24488371 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN24488371 |
| Protocol serial number | N/A |
| Sponsor | University of Twente (The Netherlands) |
| Funders | RVVZ (Reserve Voormalige Vrijwillige Ziekenfondsen) a governmental non profit health organisation (The Netherlands), Dutch Arthritis Foundation (The Netherlands) |
- Submission date
- 29/12/2006
- Registration date
- 16/01/2007
- Last edited
- 22/10/2008
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Musculoskeletal Diseases
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Prof Mart van de Laar
Scientific
Scientific
University of Twente
Institute for Behavioural Research
Department of Psychology and Communication of Health Risk (PCHR)
P.O. Box 217
Enschede
7500 AE
Netherlands
| Phone | +31 (0)53 489 2398 |
|---|---|
| m.a.f.j.vandelaar@utwente.nl |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | The DAPPER study is a randomised controlled clinical trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study acronym | DAPPER-study: Disabled Arthritis Patients Post-hospitalisation Exercise Recovery/Rehabilitation |
| Study objectives | 1. Three weeks of intensive training immediately after hospital discharge improves the functional ability, mobility, quality of life in patients with arthritis on the short term and on the long term. 2. Over a period of one year the total cost of the intensive training group are equal or lower to the usual care associated with better effectiveness. 3. The arm ergometer is a valid and reliable measuring device to measure the aerobic condition with the use of the Åstrand Rhyming test. |
| Ethics approval(s) | The trial was reviewed and accepted by the certified medical ethical commission (METC) of the Medisch Spectrum Twente in May 2002 (ref: P02-023) |
| Health condition(s) or problem(s) studied | Rheumatoid arthritis and Osteoarthritis |
| Intervention | Directly following hospital discharge the patients of this study design recieved Intensive Exercise Therapy (IET) or Usual Care (UC). The IET group were referred to a dedicated convalescent hotel. The hotel facilities and professional care for disabled people were offered for three-weeks. Thereafter, the IET group received regular care only. During their three week stay patients were trained twice a day by physical therapists, for 75 minutes per session. The goals of the training were improvement of range of motion, muscle strength, aerobic capacity and activities of daily life. The therapy sessions were given individually as well as in groups. In the first two weeks, treatment focused on individual limitations (range of motion, strength, balance, aerobic capacity and simple functionality). Aerobic capacity was trained daily on a sub maximal level. Hydrotherapy was applied after sufficient wound healing. During the third week, the training was focused on the functional capacities as prioritised by the patient. A group education program was given twice a week. This program was based on the self management training for arthritis patients by Kate Lorig modified for the Netherlands by Taal. In contrast, the patients in the UC group received usual care at the discretion of their attending physician only. Usual care consists of either physical therapy by a local physical therapist or temporary admission to a nursing home, when applicable. |
| Intervention type | Other |
| Primary outcome measure(s) |
Function ability as measured with the McMaster Toronto Arthritis patient preference questionnaire (MACTAR) and Health Assessment Questionnaire (HAQ). |
| Key secondary outcome measure(s) |
1. Quality of life as measured with the RAND-36/Short Form health survey (SF-36) and Arthritis Impact Measurement Scales (AIMS) |
| Completion date | 05/01/2005 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Lower age limit | 18 Years |
| Sex | Not Specified |
| Target sample size at registration | 130 |
| Key inclusion criteria | 1. Aged over 18 2. Rheumatoid Arthritis (RA) according to the American College of Rheumatology (ACR) 1987 or polyarticular OsteoArthritis (OA) |
| Key exclusion criteria | 1. Presence of serious cardiac disease (New York Heart Association [NYHA] class III and IV) 2. Incapacitating pulmonary disease Global initiative for chronic Obstructive Lung Disease (GOLD) stage IV 3. Serious hypertension (diastolic blood pressure more than 110 mmHg) 4. Pregnancy 5. Insufficient understanding of the Dutch language 6. Functional incapacity (Steinbrocker functional class four) |
| Date of first enrolment | 01/01/2002 |
| Date of final enrolment | 05/01/2005 |
Locations
Countries of recruitment
- Netherlands
Study participating centre
University of Twente
Enschede
7500 AE
Netherlands
7500 AE
Netherlands
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 15/02/2008 | Yes | No |
