Investigation of treatment of algodystrophy by guanethidine blockade

ISRCTN	ISRCTN24808507
DOI	https://doi.org/10.1186/ISRCTN24808507
Protocol serial number	A0053
Sponsor	Arthritis Research Campaign (ARC) (UK)
Funder	Arthritis Research Campaign (UK)

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Mr JA Livingstone
Scientific

Department of Orthopaedic Surgery
Bristol Royal Infirmary
Marlborough Street
Bristol
BS2 9HW
United Kingdom

Phone	+44 (0)117 9282658

Primary study design	Interventional
Study design	Randomised controlled trial
Secondary study design	Randomised controlled trial
Scientific title
Study objectives	Not provided at time of registration
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Reflex sympathetic dystrophy
Intervention	Intravenous regional (Biers) block to the affected arm using either: 1. 30 ml normal saline, or 2. 15 mg guanethidine in 30 ml 0.5% pritocaine
Intervention type	Drug
Phase	Not Specified
Drug / device / biological / vaccine name(s)	15 mg guanethidine in 30 ml 0.5% pritocaine
Primary outcome measure(s)	Not provided at time of registration
Key secondary outcome measure(s)	Not provided at time of registration
Completion date	01/01/2001

Participant type(s)	Patient
Age group	Not Specified
Sex	Not Specified
Key inclusion criteria	Closed, unilateral fracture of the distal radius
Key exclusion criteria	Not provided at time of registration
Date of first enrolment	01/01/1999
Date of final enrolment	01/01/2001

Department of Orthopaedic Surgery

Bristol
BS2 9HW
United Kingdom

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	Results	01/04/2002		Yes	No