Horizon 2020 Project ValueCare: Value-based methodology for integrated care supported by Information and Communication Technology

1. Approved 26/11/2021, Medische Ethische Commissie (MEC) – Erasmus Medical Center Rotterdam (Erasmus MC, Room Ae-337, Dr. Molewaterplein 40, Rotterdam, 3015 GD, Netherlands; +31 (0)10-70 34428, +31 (0)10-70 33625; metc@erasmusmc.nl), ref: 20210727

2. Approved 18/04/2022, Ethics and Conduct committee (Athens Medical Center, Athens, 15125, Greece; +30 2106198100; info@iatriko.gr), ref: Ε.Σ. 86/ 12-04-22

3. Approved 24/03/2022, Comissão da Administração Regional de Saúde do Centro (no address provided, Coimbra, no zip code provided, Portugal; no telephone number provided; noemail@provided), ref: 13-2022

4. Approved 11/08/2021, University College Dublin Human Research Ethics Committee (UCD HREC) and Clinical Research Ethics Commit tee of the Cork Teaching Hospital (CREC) (no address provided, Cork, no zip code provided, Ireland; no telephone number provided; noemail@provided), ref: LS-21-69-Darley

5. Approved 31/08/2021, The Ethical Committee—Faculty of Medicine, University of Rijeka (no address provided, Rijeka, no zip code provided, Croatia; no telephone number provided; noemail@provided), ref: 2170-24-04-3-21-11

6. Approved 03/03/2022, Comitato Etico per Sperimentazione Clinica delle province di Treviso e Belluno (no address provided, Treviso, no zip code provided, Italy; no telephone number provided; noemail@provided), ref: 1159/CE Marca

7. Approved 07/05/2020, Comisión de Ética en Investigación Experimental de la Universitat de València (no address provided, Valencia, no zip code provided, Spain; no telephone number provided; noemail@provided), ref: no ref provided

Health-related quality of life (HR-QoL) score measured using the PROMIS Scale v1.2 – Global Health (PROMIS-10) at baseline, 12, and 18 months

1. Loneliness measured using the UCLA 3-Item Loneliness Scale (Hughes et al., 2004) at baseline, 12, and 18 months
2. Alcohol consumption measured using one item of the International Consortium for Health Outcomes Measurement (ICHOM, 2016) at baseline, 12, and 18 months
3. Smoking status measured using one item of the ICHOM at baseline, 12, and 18 months
4. Nutrition and undernutrition measured using the SNAQ65+ (Wijnhoven et al., 2012) at baseline, 12, and 18 months
5. Physical activity measured using one item of the SHARE-Frailty instrument (Romero-Ortuno, 2011) and one item of the Internal Physical Activity Questionnaire (IPAQ) on sitting time (Lee et al., 2011) at baseline, 12, and 18 months
6. Frailty measured using the 15-item Tilburg Frailty Indicator (Gobbens, 2010) at baseline, 12, and 18 months
7. Falls-related quality of life measured using the reported number of falls in the previous year and fear of falling on the Visual Analogue Scale for Fear of Falling (Chang & Ganz, 2007) at baseline, 12, and 18 months
8. Medication intake and use measured using the Medication Risk Questionnaire (MRQ-10) (Barenholtz Levy, 2003) at baseline, 12, and 18 months
9. Activities of daily living measured using the modified 10-item Barthel Index (Collin et al., 1988) at baseline, 12, and 18 months
10. Co-morbidities measured using one item of the ICHOM at baseline, 12, and 18 months
11. Health and social care utilization measured using the modified SMRC Health Care Utilization questionnaire (Lorig et al. 2001) at baseline, 12, and 18 months
12. Time spent on providing informal care measured using the iMTA Valuation of Informal Care Questionnaire (iVICQ) (Hoefman et al., 2013) at baseline, 12, and 18 months
13. Carer burden measured using the 4-item Zarit Burden Interview (ICHOM, 2016; Bedard et al., 2001) at baseline, 12, and 18 months
14. Control over daily life measured using the Adult Social Care Outcomes Toolkit (Netten et al., 2012) at baseline, 12, and 18 months
15. Working conditions of care team practitioners measured using the Culture of Care Barometer tool (Rafferty et al., 2017) at baseline, 12, and 18 months
16. Job satisfaction of care team members measured using the Minnesota Satisfaction Questionnaire - Short Form (Weiss et al., 1977) at baseline, 12, and 18 months
17. Work-related burnout measured using the Copenhagen Burnout Inventory (Kristensen et al., 2005) at baseline, 12, and 18 months
18. Body Mass Index (BMI) measured by asking about length and weight (ICHOM, 2016) at baseline, 12 and 18 months
19. Quality of life measured using the EQ-5D-5L measure (Herdman et al., 2011) at baseline, 12 and 18 months

Cost measures:
1. Productivity losses measured using the iMTA Productivity Cost Questionnaire (iPCQ) (Bouwmans et al., 2015) at 18 months

Implementation outcomes will be measured in terms of acceptability, appropriateness, feasibility, fidelity, and costs.