A study to investigate the effect of probiotics on faecal flora - does administration of the probiotic 'Acidophilus' reduce counts of Enterobacteriaceae in the intestines of healthy volunteers?
| ISRCTN | ISRCTN26317136 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN26317136 |
| Protocol serial number | N0012128241 |
| Sponsor | Department of Health |
| Funders | Great Ormond Street Hospital for Children, Institute of Child Health, University College London |
- Submission date
- 30/09/2004
- Registration date
- 30/09/2004
- Last edited
- 28/11/2014
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Infections and Infestations
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr J S Soothill
Scientific
Scientific
Microbiology
Great Ormond Street Hospital
Great Ormond Street
London
WC1N 3JH
United Kingdom
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | A study to investigate the effect of probiotics on faecal flora - does administration of the probiotic 'Acidophilus' reduce counts of Enterobacteriaceae in the intestines of healthy volunteers? |
| Study objectives | To investigate whether administration of a probiotic preparation reduces the carriage of Enterobacteriaceae in the gut. |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Infections and Infestations: Gram-negative bacteriae |
| Intervention | 1. Probiotics - treatment for gut infection 2. No treatment |
| Intervention type | Other |
| Primary outcome measure(s) |
Not provided at time of registration |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 30/11/2005 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Key inclusion criteria | Healthy adult volunteers |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/03/2002 |
| Date of final enrolment | 30/11/2005 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Great Ormond Street Hospital
London
WC1N 3JH
United Kingdom
WC1N 3JH
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
