Evaluation of telephone-administered cognitive-behaviour therapy (CBT) for young people with obsessive-compulsive disorder (OCD)

ISRCTN	ISRCTN27070832
DOI	https://doi.org/10.1186/ISRCTN27070832
Protocol serial number	PB-PG-0107-12333
Sponsor	Institute of Psychiatry, Kings College London (UK)
Funder	National Institute for Health Research (NIHR) (UK), Research for Patient Benefit (RfPB) Programme (ref: PB-PG-0107-12333)

Submission date: 14/08/2008
Registration date: 18/09/2008
Last edited: 22/10/2015

Recruitment status: No longer recruiting
Overall study status: Completed
Condition category: Mental and Behavioural Disorders

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Dr Cynthia Turner
Scientific

Obsessive-Compulsive and Related Disorders Clinic
Michael Rutter Centre for Children and Young People
Maudsley Hospital
De Crespigny Park
London
SE5 8AZ
United Kingdom

Email	cynthia.turner@slam.nhs.uk

Study information

Primary study design	Interventional
Study design	Randomised single-centre single-blind non-inferiority controlled trial
Secondary study design	Randomised controlled trial
Study type	Participant information sheet
Scientific title	An evaluation of the clinical effectiveness, cost-effectiveness and acceptability of a telephone-administered cognitive-behaviour therapy (CBT) programme for children and young people with obsessive-compulsive disorder (OCD)
Study objectives	1. The clinical outcome of cognitive-behaviour therapy (CBT) delivered by telephone will be equivalent to CBT treatment delivered face-to-face in the treatment of childhood OCD 2. Telephone CBT for young people will be a cost-effective means of service delivery 3. Young people and their families will find this treatment acceptable and convenient
Ethics approval(s)	The Joint South London and Maudsley and the Institute of Psychiatry NHS Research Ethics Committee, 25/03/2008, ref: 08/H0807/12
Health condition(s) or problem(s) studied	Obsessive-compulsive disorder (OCD)
Intervention	Participants will be randomly allocated to receive either face-to-face CBT or telephone-administered CBT. All participants will receive up to 14 sessions of CBT within 17 weeks (each CBT session lasts approximately 55 minutes).
Intervention type	Other
Primary outcome measure(s)	The following will be measured at assessment, baseline, post-treatment, 3-month, 6-month and 12-month follow-up: 1. A diagnosis of OCD, as measured by the Anxiety Disorders Interview Schedule for DSM-IV Parent/Child Versions (ADIS-IV-C/P) 2. The severity of OCD symptoms, as measured by the Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS)
Key secondary outcome measure(s)	The following will be measured at assessment, baseline, post-treatment, 3-month, 6-month and 12-month follow-up: 1. Children's Obsessive-Compulsive Inventory (ChOCI C/P) 2. Strengths and Difficulties Questionnaire (SDQ) 3. Beck Depression Inventory for Youth (BDI-Y) 4. Depression, Anxiety and Stress Scales (DASS) 5. Family Accommodation Scale (FAS) 6. Children's Global Assessment Scale (CGAS) 7. Child and Adolescent Service Use Schedule (CA-SUS) 8. EuroQol-5D (EQ-5D)
Completion date	30/09/2011

Eligibility

Participant type(s)	Patient
Age group	Child
Lower age limit	11 Years
Upper age limit	18 Years
Sex	All
Target sample size at registration	80
Key inclusion criteria	1. Both males and females, age 11 to 18 years 2. Primary Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) diagnosis of OCD 3. Stable medication for 12 weeks (if relevant) 4. Access to a telephone
Key exclusion criteria	1. Current diagnosis of psychosis, current alcohol or substance abuse/dependence 2. English too poor to engage in treatment without an interpreter being required 3. Severe disabling neurological disorder 4. A diagnosed global learning disability or pervasive developmental delay 5. Characteristics interfering with completion of treatment e.g. life-threatening or unstable medical illness
Date of first enrolment	01/09/2008
Date of final enrolment	30/09/2011

Locations

Countries of recruitment

United Kingdom
England

Study participating centre

Maudsley Hospital

London
SE5 8AZ
United Kingdom

Results and Publications

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan

Study outputs

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	01/12/2014		Yes	No
Participant information sheet	Participant information sheet	11/11/2025	11/11/2025	No	Yes