The effect of a protective ventilation strategy, fine tuned using pulmonary mechanics monitoring, on outcome from severe acute respiratory failure in children
| ISRCTN | ISRCTN27628446 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN27628446 |
| Secondary identifying numbers | N0012027897 |
- Submission date
- 12/09/2003
- Registration date
- 12/09/2003
- Last edited
- 16/09/2009
- Recruitment status
- Stopped
- Overall study status
- Stopped
- Condition category
- Respiratory
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr M Schindler
Scientific
Scientific
PICU
Great Ormond Street Hospital
Great Ormond Street
London
WC1N 3JH
United Kingdom
| Phone | +44 (0)20 7813 8213 |
|---|---|
| Margrid.Schindler@gosh-tr.nthames.nhs.uk |
Study information
| Study design | Randomised controlled trial |
|---|---|
| Primary study design | Interventional |
| Secondary study design | Randomised controlled trial |
| Study setting(s) | Hospital |
| Study type | Treatment |
| Scientific title | |
| Study objectives | Does the use of pulmonary function testing to adjust ventilation parameters improve outcome from acute paediatric respiratory failure? |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Respiratory: Acute paediatric respiratory failure |
| Intervention | Please note that as of 16/09/09 the status of this record was changed to "Stopped" due to lack of funding. There is no plan to recommence the trial. Randomised controlled trial. Random allocation to (A) Pulmonary function testing (B) Standard care. |
| Intervention type | Other |
| Primary outcome measure | Survival at 28 days. |
| Secondary outcome measures | Not provided at time of registration |
| Overall study start date | 01/03/1999 |
| Completion date | 24/05/2003 |
| Reason abandoned (if study stopped) | Lack of funding/sponsorship |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Child |
| Sex | Both |
| Target number of participants | Not provided at time of registration |
| Key inclusion criteria | Children with severe acute respiratory failure. |
| Key exclusion criteria | Does not match inclusion criteria |
| Date of first enrolment | 01/03/1999 |
| Date of final enrolment | 24/05/2003 |
Locations
Countries of recruitment
- England
- United Kingdom
Study participating centre
PICU
London
WC1N 3JH
United Kingdom
WC1N 3JH
United Kingdom
Sponsor information
Department of Health (UK)
Government
Government
Richmond House
79 Whitehall
London
SW1A 2NL
United Kingdom
| Website | http://www.doh.gov.uk |
|---|
Funders
Funder type
Hospital/treatment centre
Great Ormond Street Hospital for Children NHS Trust / Institute of Child Health (UK)
No information available
Results and Publications
| Intention to publish date | |
|---|---|
| Individual participant data (IPD) Intention to share | No |
| IPD sharing plan summary | Not provided at time of registration |
| Publication and dissemination plan | Not provided at time of registration |
| IPD sharing plan |
