Metformin in women with cardiac syndrome X: a randomised double blind placebo controlled trial
| ISRCTN | ISRCTN28863939 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN28863939 |
| Protocol serial number | PG/99124 |
| Sponsor | British Heart Foundation |
| Funder | British Heart Foundation (UK) |
- Submission date
- 31/01/2002
- Registration date
- 31/01/2002
- Last edited
- 10/09/2007
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Circulatory System
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr N Sattar
Scientific
Scientific
University Department of Pathological Biochemistry
Glasgow Royal Infirmary
Glasgow
G31 2ER
United Kingdom
| Phone | +44 (0)141 211 4312 |
|---|---|
| nsattar@clinmed.gla.ac.uk |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | Not provided at time of registration |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Cardiac syndrome X |
| Intervention | 1. Metformin 500 mg twice daily (BD) 2. Matching placebo 1 tab BD Both treatments will continue for 8 weeks. |
| Intervention type | Drug |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | Metformin |
| Primary outcome measure(s) |
Not provided at time of registration |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/01/2001 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Female |
| Key inclusion criteria | Women, post menopausal but less than 70 years with Cardiac Syndrome X (definition angina/positive exercise test/normal coronary arteriogram) |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/01/1997 |
| Date of final enrolment | 01/01/2001 |
Locations
Countries of recruitment
- United Kingdom
- Scotland
Study participating centre
University Department of Pathological Biochemistry
Glasgow
G31 2ER
United Kingdom
G31 2ER
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | Results | 05/09/2006 | Yes | No |
