Resistance training and leucine supplementation : effects on performance and body composition of untrained subjects.
| ISRCTN | ISRCTN31209884 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN31209884 |
| Protocol serial number | N0436146689 |
| Sponsor | Department of Health |
| Funders | Leeds Teaching Hospitals NHS Trust (UK), NHS R&D Support Funding |
- Submission date
- 30/09/2005
- Registration date
- 30/09/2005
- Last edited
- 23/08/2012
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Nutritional, Metabolic, Endocrine
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Mr T Ispoglou
Scientific
Scientific
School of leisure and sports studies
Calverley Street
Leeds
LS1 3HE
United Kingdom
| Phone | +44 (0)113 2832600 |
|---|
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised placebo controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study objectives | To investigate whether long-term leucine supplementation in combination with resistance training can induce higher increases in strength and muscle mass of untrained subjects compared to a placebo group undertaking resistance training only. To investigate potential decreases in muscle mass after four weeks following the end of the supplementation period |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Nutritional, Metabolic, Endocrine: Leucine supplementation |
| Intervention | Randomised controlled trial |
| Intervention type | Other |
| Primary outcome measure(s) | Bone density |
| Key secondary outcome measure(s) | Not provided at time of registration |
| Completion date | 01/09/2004 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Adult |
| Sex | Male |
| Target sample size at registration | 30 |
| Key inclusion criteria | Healthy male subjects |
| Key exclusion criteria | 1. Athletes or trained subjects 2. Having diabetes 3. Heart disease 4. High blood pressure or any other chronic or serious illness 5. Having taken anabolic steroids or any other sports supplements at least 2 months before the beginning of the study |
| Date of first enrolment | 01/12/2003 |
| Date of final enrolment | 01/09/2004 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
School of leisure and sports studies
Leeds
LS1 3HE
United Kingdom
LS1 3HE
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | results | 01/03/2011 | Yes | No |
