The clinical and immunohistochemical effect of UVA-1 phototherapy on discoid lupus erythematosus (DLE): a randomised controlled trial
| ISRCTN | ISRCTN31313147 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN31313147 |
| Protocol serial number | N0436186543 |
| Sponsor | Record Provided by the NHSTCT Register - 2007 Update - Department of Health |
| Funders | Leeds Teaching Hospitals NHS Trust (UK), NHS R&D Support Funding |
- Submission date
- 28/09/2007
- Registration date
- 28/09/2007
- Last edited
- 03/02/2015
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Skin and Connective Tissue Diseases
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Record updated in last year
Plain English summary of protocol
Not provided at time of registration
Contact information
Dr David Fairhurst
Scientific
Scientific
Department of Dermatology
Dawson Floor
Brotherton Wing
Great George Street
Leeds
LS1 3EX
United Kingdom
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Study type | Participant information sheet |
| Scientific title | The clinical and immunohistochemical effect of UVA-1 phototherapy on discoid lupus erythematosus (DLE): a randomised controlled trial |
| Study objectives | 1. To ascertain whether or not UVA-1 phototherapy improves DLE 2. To ascertain what immunohistochemical changes occur in DLE lesions following UVA-1 phototherapy |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Skin and Connective Tissue Diseases: Discoid lupus erythematosus (DLE) |
| Intervention | Phototherapy vs standard therapy |
| Intervention type | Procedure/Surgery |
| Primary outcome measure(s) |
1. Improvement in DLE after UVA-1 phototherapy |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/02/2008 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Key inclusion criteria | Patients with DLE attending the Dermatology Department |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/08/2006 |
| Date of final enrolment | 01/02/2008 |
Locations
Countries of recruitment
- United Kingdom
- England
Study participating centre
Department of Dermatology
Leeds
LS1 3EX
United Kingdom
LS1 3EX
United Kingdom
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Participant information sheet | Participant information sheet | 11/11/2025 | 11/11/2025 | No | Yes |
