Comparison of urokinase versus primary video-assisted thorascopic surgery for the treatment of empyema in children

ISRCTN	ISRCTN32346229
DOI	https://doi.org/10.1186/ISRCTN32346229
Protocol serial number	N0012114253
Sponsor	Department of Health (UK)
Funder	Great Ormond Street Hospital for Children NHS Trust / Institute of Child Health (UK)

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Dr A Jaffe
Scientific

Portex Unit
Institute of Child Health
30 Guilford Street
London
WC1N 1EH
United Kingdom

Phone	+44 (0)20 7405 9200

Primary study design	Interventional
Study design	Randomised controlled trial
Secondary study design	Randomised controlled trial
Scientific title
Study objectives	Is primary video-assisted thorascopic surgery (VATS) the treatment of choice for empyema in children?
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Respiratory: Empyema
Intervention	Random allocation to (A) Treatment for empyema (B) Placebo.
Intervention type	Other
Primary outcome measure(s)	Number of hospital days post procedure until ready for discharge.
Key secondary outcome measure(s)	1. Total length of hospital stay 2. Total length of illness 3. Number of chest tube days
Completion date	31/01/2005

Participant type(s)	Patient
Age group	Child
Sex	Not Specified
Key inclusion criteria	Children with empyema.
Key exclusion criteria	Not provided at time of registration
Date of first enrolment	01/02/2002
Date of final enrolment	31/01/2005

Portex Unit

London
WC1N 1EH
United Kingdom

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	15/07/2006		Yes	No