Prevention by epidural Injection of postherpetic Neuralgia in the Elderly
| ISRCTN | ISRCTN32866390 |
|---|---|
| DOI | https://doi.org/10.1186/ISRCTN32866390 |
| Protocol serial number | NWO 945-02-009 |
| Sponsor | Julius Center for Health Sciences and Primary Care (The Netherlands) |
| Funder | The Netherlands Organisation for Scientific Research (The Netherlands) (ref: 945-02-009) |
- Submission date
- 23/10/2003
- Registration date
- 24/11/2003
- Last edited
- 31/03/2010
- Recruitment status
- No longer recruiting
- Overall study status
- Completed
- Condition category
- Infections and Infestations
Prospectively registered
Protocol
Statistical analysis plan
Results
Individual participant data
Plain English summary of protocol
Not provided at time of registration
Contact information
Prof Theo Verheij
Scientific
Scientific
Julius Center for Health Sciences and Primary Care
University Medical Center
PO Box 85060
Utrecht
3500 AB
Netherlands
| Phone | +31 (0)30 253 8188 |
|---|---|
| T.J.M.Verheij@med.uu.nl |
Study information
| Primary study design | Interventional |
|---|---|
| Study design | Randomised controlled trial |
| Secondary study design | Randomised controlled trial |
| Scientific title | |
| Study acronym | PINE |
| Study objectives | Not provided at time of registration |
| Ethics approval(s) | Not provided at time of registration |
| Health condition(s) or problem(s) studied | Herpes zoster/postherpetic neuralgia |
| Intervention | Index group: Standard treatment (antiviral and analgesic medication) plus epidural injection of local anaesthetics and corticosteroids. Control group: Standard treatment (antiviral and analgesic medication) |
| Intervention type | Drug |
| Phase | Not Specified |
| Drug / device / biological / vaccine name(s) | Methylprednisolone-acetate, bupivacaine |
| Primary outcome measure(s) |
Not provided at time of registration |
| Key secondary outcome measure(s) |
Not provided at time of registration |
| Completion date | 01/01/2005 |
Eligibility
| Participant type(s) | Patient |
|---|---|
| Age group | Not Specified |
| Sex | Not Specified |
| Target sample size at registration | 550 |
| Key inclusion criteria | Elderly patients (age >50 years) with acute herpes zoster (skin lesions <7 days) below dermatome C6 in primary care |
| Key exclusion criteria | Not provided at time of registration |
| Date of first enrolment | 01/01/2004 |
| Date of final enrolment | 01/01/2005 |
Locations
Countries of recruitment
- Netherlands
Study participating centre
Julius Center for Health Sciences and Primary Care
Utrecht
3500 AB
Netherlands
3500 AB
Netherlands
Results and Publications
| Individual participant data (IPD) Intention to share | No |
|---|---|
| IPD sharing plan summary | Not provided at time of registration |
| IPD sharing plan |
Study outputs
| Output type | Details | Date created | Date added | Peer reviewed? | Patient-facing? |
|---|---|---|---|---|---|
| Results article | Results | 21/01/2006 | Yes | No | |
| Protocol article | Protocol | 26/01/2004 | Yes | No |
