A comparison of warfarin and aspirin for stroke prevention in octogenarians in atrial fibrillation study

ISRCTN	ISRCTN36280307
DOI	https://doi.org/10.1186/ISRCTN36280307
Protocol serial number	N0164097348
Sponsor	Department of Health (UK)
Funder	Northern General Hospital NHS Trust (UK)

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Dr KS Channer
Scientific

Royal Hallamshire Hospital NHS Trust
M Floor
Glossop Road
Sheffield
S10 2JF
United Kingdom

Phone	+44 (0)114 271 3473

Primary study design	Interventional
Study design	Randomised controlled trial
Secondary study design	Randomised controlled trial
Scientific title
Study objectives	To determine whether warfarin or aspirin is better in the prevention of strokes.
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Cardiovascular: Stroke
Intervention	Wwarfarin or aspirin
Intervention type	Other
Primary outcome measure(s)	1. Comparative frequency of embolic events 2. Comparative frequency of serious bleeding 3. Death 4. Refusal to continue 5. Adverse events
Key secondary outcome measure(s)	Not provided at time of registration
Completion date	24/04/2003

Participant type(s)	Patient
Age group	Not Specified
Sex	Not Specified
Target sample size at registration	200
Key inclusion criteria	200 patients in total aged between 80 and 89 years, with persistant or permanent atrial fibrillation.
Key exclusion criteria	Not provided at time of registration
Date of first enrolment	24/04/2001
Date of final enrolment	24/04/2003

Royal Hallamshire Hospital NHS Trust

Sheffield
S10 2JF
United Kingdom

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	01/03/2007		Yes	No