Acceptance and cost effectiveness of insecticide treated curtains in areas with low Aedes infestation levels

ISRCTN	ISRCTN37433764
DOI	https://doi.org/10.1186/ISRCTN37433764
Protocol serial number	EC UZA 8/36/196
Sponsor	Institute of Tropical Medicine (Belgium)
Funders	Directorate General for Development Cooperation (DGDC) (Belgium) (project ref: 95900) (framework agreement between the Institute of Tropical Medicine of Belgium and of Cuba), Ministry of Health (MINSAP) (Cuba)

Submission date: 08/03/2011
Registration date: 04/05/2011
Last edited: 21/01/2019

Recruitment status: No longer recruiting
Overall study status: Completed
Condition category: Infections and Infestations

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Plain English summary of protocol

Not provided at time of registration

Contact information

Prof Patrick Van der Stuyft
Scientific

Nationale Straat 155
Antwerp
2000
Belgium

Study information

Primary study design	Interventional
Study design	Single-centre cluster randomised controlled trial
Secondary study design	Cluster randomised trial
Study type	Participant information sheet
Scientific title	Acceptance and cost effectiveness of insecticide treated curtains in areas with low Aedes infestation levels: a single-centre, cluster, randomised controlled trial
Study objectives	Acceptance, effectiveness and cost effectiveness of a dengue control intervention implementing insecticide treated curtains, as a single Aedes control strategy will be different than when implementation of curtains is combined with community based environmental management.
Ethics approval(s)	Ethical committee of University Hospital Antwerp, 15/09/2008
Health condition(s) or problem(s) studied	Effect of intervention on Aedes aegypti infestation levels (vector of dengue fever)
Intervention	1. Insecticide treated curtains: made from long-lasting, insecticide treated (pyrethroid deltamethrin is applied during manufacture) polyester netting that requires no re-impregnation, materials are special ultraviolet (UV) protected and retain their insecticidal properties and efficacy for about 2 years (information from producer). 2. The material has been approved by World Health Organisation Pesticide Evaluation Scheme (WHOPES) for use as bednets. 3. Community based environmental management approach: dengue control activities were identified, designed, planned and executed by the community itself, with the support of newly set up local 'community working groups' 4. Control: routine aedes control programme (entomological surveillance, source reduction, selective adulticiding and health education)
Intervention type	Other
Primary outcome measure(s)	1. Aedes infestation levels are the primary outcomes 1.1. House Indices (HI) - number of houses positive for at least one container with Aedes aegypti immature stages/100 inspected houses 1.2. Breteau Indices (BI) number of containers positive for Aedes. aegypti immature stages/100 inspected houses 1.3. Pupal Indices (PI) number of Aedes. aegypti pupae/inhabitant 2. In cycles of 11 days, the National Vector Control programme conduct routine entomological surveys in all dwellings of the municipality. This will provide the entomological information for all clusters for the period of study.
Key secondary outcome measure(s)	1. Uptake, use and acceptance of Insecticide treated curtains 2. Financial cost of the two interventions in comparison to the control 3. The percentage of blocks repeatedly positive for larvae 4. Level of community participation based on Rifkin criteria
Completion date	01/04/2012

Eligibility

Participant type(s)	Patient
Age group	Not Specified
Sex	All
Target sample size at registration	500
Key inclusion criteria	1. No patients, but communities were included 2. Circumscriptions (neighboorhoods) of urban Guantanamo after obtaining community approval
Key exclusion criteria	Circumscriptions without community approval
Date of first enrolment	30/09/2008
Date of final enrolment	01/04/2012

Locations

Countries of recruitment

Belgium
Cuba

Study participating centre

Nationale Straat 155

Antwerp
2000
Belgium

Results and Publications

Individual participant data (IPD) Intention to share	Yes
IPD sharing plan summary	Available on request
IPD sharing plan	The datasets generated and analysed during the current study are available upon request from Toledo Maria Eugenia (mariaeugenia@ipk.sld.cu), Institute of Tropical Medicine “Pedro Kourí”, Habana, Cuba. Data sharing may be conditional on approval of the purported use by the Cuban Ministry of Health.

Study outputs

Output type	Details	Date created	Date added	Peer reviewed?	Patient-facing?
Results article	results	20/03/2015	17/01/2019	Yes	No
Participant information sheet	Participant information sheet	11/11/2025	11/11/2025	No	Yes

Editorial Notes

21/01/2019: IPD sharing statement.
17/01/2019: Publication reference added.