A randomised, double-blind, controlled trial to investigate the effect of topically applied plant oils on thermal pain and detection thresholds

ISRCTN	ISRCTN38182937
DOI	https://doi.org/10.1186/ISRCTN38182937
Protocol serial number	N0263092936
Sponsor	Department of Health (UK)
Funder	University College London Hospitals NHS Trust (UK)

Prospectively registered

Protocol

Statistical analysis plan

Results

Individual participant data

Record updated in last year

Plain English summary of protocol

Not provided at time of registration

Dr S Davies
Scientific

Pain Management Department
National Hospital for Neurology & Neurosurgery
Queen Square
London
WC1N 3BG
United Kingdom

Phone	+44 (0)20 7837 3611

Primary study design	Interventional
Study design	Randomised controlled trial
Secondary study design	Randomised controlled trial
Scientific title
Study objectives	Does peppermint oil significantly affect thermal detection and pain thresholds?
Ethics approval(s)	Not provided at time of registration
Health condition(s) or problem(s) studied	Respiratory: Thermal pain
Intervention	1. Active peppermint oil 2. Placebo oil
Intervention type	Drug
Phase	Not Applicable
Drug / device / biological / vaccine name(s)	Peppermint oil
Primary outcome measure(s)	1. Cold detection threshold 2. Warm detection threshold 3. Cold pain threshold 4. Heat pain threshold.
Key secondary outcome measure(s)	Not provided at time of registration
Completion date	01/06/2005

Participant type(s)	Patient
Age group	Not Specified
Sex	Not Specified
Key inclusion criteria	Volunteers
Key exclusion criteria	Not provided at time of registration
Date of first enrolment	05/03/2001
Date of final enrolment	01/06/2005

Pain Management Department

London
WC1N 3BG
United Kingdom

Individual participant data (IPD) Intention to share	No
IPD sharing plan summary	Not provided at time of registration
IPD sharing plan